ICCAS OpenIR
Synthesis of ficin-protected AuNCs in a droplet-based microreactor for sensing serum ferric ions
Wu, Han; Qiao, Juan; Hwang, Yoon-Ho; Xu, Chengnan; Yu, Tian; Zhang, Rongyue; Cai, Huiwu; Kim, Dong-Pyo; Qi, Li
2019-08-01
Source PublicationTALANTA
ISSN0039-9140
Volume200Pages:547-552
AbstractA droplet-based microfluidic synthesis approach for preparation of ficin capped gold nano clusters (AuNCs) was developed. Well dispersed AuNCs could be procured within 8 min. Upon excitation wavelength at 340 nm, the resultant AuNCs exhibited a strong blue fluorescence with the maximum emission at 450 mm Due to the aggregation-induced "turn-off' fluorescence mechanism, the synthesized AuNCs as a fluorescent probe displayed high sensitivity and good selectivity for sensing ferric ions. The relative fluorescence intensity versus ferric ions concentration yielded a good linear calibration in the range of 10.0-1000.0 mu M (R-2 = 0.998) and the limit of detection was 4.1 mu M. Moreover, the possible mechanism for abated fluorescence intensity of AuNCs by adding ferric ions was discussed briefly. Further, the as-prepared fluorescent AuNCs was successfully applied for the detection of serum ferric ions. The results indicated that the droplet-based microfluidic synthesis system could provide a new way for the rapid preparation of AuNCs with good polydispersity and have potential as the sensing probes for the analysis of ferric ions in real biological samples.
DOI10.1016/j.talanta.2019.03.077
Indexed BySCI
Language英语
WOS IDWOS:000468715300067
EI Accession Number1873-3573
Citation statistics
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/82716
Collection中国科学院化学研究所
AffiliationChinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Wu, Han,Qiao, Juan,Hwang, Yoon-Ho,et al. Synthesis of ficin-protected AuNCs in a droplet-based microreactor for sensing serum ferric ions[J]. TALANTA,2019,200:547-552.
APA Wu, Han.,Qiao, Juan.,Hwang, Yoon-Ho.,Xu, Chengnan.,Yu, Tian.,...&Qi, Li.(2019).Synthesis of ficin-protected AuNCs in a droplet-based microreactor for sensing serum ferric ions.TALANTA,200,547-552.
MLA Wu, Han,et al."Synthesis of ficin-protected AuNCs in a droplet-based microreactor for sensing serum ferric ions".TALANTA 200(2019):547-552.
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