ICCAS OpenIR
In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy
Xu, YZ; Zhang, YF; Yang, LM; Peng, X; Sun, KH; Li, QB; Zhou, WJ; Wu, HZ; Yu, GY; Liu, Z; Weng, SF; Wang, J; Ying, Z; Xu, DF; Wu, JG
2004-02-01
Source PublicationCHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
ISSN0251-0790
Volume25Issue:2Pages:348-350
AbstractOur previous studies show that mid-FTIR spectroscopy can be used to distinguish malignant oral tissue from normal tissue under in vitro condition. Here, an in-situ FTIR spectroscopic measurement was performed to record FTIR spectra of normal and malignant oral tissues including salivary gland, tongue, parotid gland, submandibular gland etc. during clinical examination. The FTIR spectra of various oral tissues were acquired when an ATR probe linked to the FTIR. spectrometer via mid-IR optical fibers was pressed on the tissues of the patients. For example, a patient(male, 76 years old) with tumor on the left parotid and the corresponding normal tissue on the right parotid were measured and obvious differences were observed. The spectral features of normal tissue and tumor are in good agreement with the criteria established in our previous work. (1) 1389 cm(-1) band is quite strong in tumor, while the corresponding band in normal tissue is weaker than 1452 cm(-1) band. (2) In normal tissue, 1250 cm(-1) band is stronger, but the 1250 cm(-1) band disappeared in the skin. of malignant tissue. The above results demonstrate that in vivo FTIR spectra are in good agreement with our previous results obtained under in vitro condition. We believe that in vivo FTIR spectroscopy, providing the first-hand information concerning whether the suspected tissue is cancerous or not, is helpful for doctors in clinical activity.
KeywordMid-ir Fiber Optics Ftir Malignancy Tumor Of Oral Tissue In Vivo And In Situ Detection
Indexed BySCI
Language英语
WOS IDWOS:000189187400039
PublisherHIGHER EDUCATION PRESS
Citation statistics
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/81974
Collection中国科学院化学研究所
Corresponding AuthorXu, YZ
Affiliation1.Peking Univ, State Key Lab Rare Earth Mat & Applicat, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
2.Peking Univ, Med Sch Stomatol, Beijing 100081, Peoples R China
3.Beijing Secondary Opt Instrument Factory, Beijing 100015, Peoples R China
4.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Xu, YZ,Zhang, YF,Yang, LM,et al. In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2004,25(2):348-350.
APA Xu, YZ.,Zhang, YF.,Yang, LM.,Peng, X.,Sun, KH.,...&Wu, JG.(2004).In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,25(2),348-350.
MLA Xu, YZ,et al."In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 25.2(2004):348-350.
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