ICCAS OpenIR
Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field
Wan, YQ; Yang, J; Yang, JL; Bei, JZ; Wang, SG
2003-09-01
Source PublicationBIOMATERIALS
ISSN0142-9612
Volume24Issue:21Pages:3757-3764
AbstractA series of gases were used for plasma treatment of poly-(L-lactide) (PLLA) under various conditions such as atmosphere, electric power, pressure and time. The NH3 was preferably selected for modifying the surface of PLLA because it can obtain appropriate hydrophilicity and surface energy with high polar component compared to other gases. Subsequently, cells were seeded onto NH3 modified surface and exposed to 29.5 N/m(2) of shear stress field by means of a parallel plate flow chamber in order to get good insight into the influence of N-containing incorporation on cell retention, cell morphology, and cell shape factor. The results showed that cell retention on the modified PLLA was much higher than that on the unmodified one. The NH3 plasma modified PLLA with high cell affinity and resistance to shear stress was gained. Surface hydrophilicity, surface energy with high polar component and N-containing groups may play an important role in enhancing cell resistance to shear stress. It revealed that the parallel plate flow chamber is an effective device for evaluating the effects of surface modification on the cell affinity of a material. (C) 2003 Elsevier Science Ltd. All rights reserved.
KeywordPoly-(L-lactide) Plasma Treatment Surface Modification Shear Stress Tissue Engineering
DOI10.1016/S0142-9612(03)00251-2
Indexed BySCI
Language英语
WOS IDWOS:000183992700014
PublisherELSEVIER SCI LTD
Citation statistics
Cited Times:127[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/81468
Collection中国科学院化学研究所
Corresponding AuthorWang, SG
AffiliationChinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Wan, YQ,Yang, J,Yang, JL,et al. Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field[J]. BIOMATERIALS,2003,24(21):3757-3764.
APA Wan, YQ,Yang, J,Yang, JL,Bei, JZ,&Wang, SG.(2003).Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field.BIOMATERIALS,24(21),3757-3764.
MLA Wan, YQ,et al."Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field".BIOMATERIALS 24.21(2003):3757-3764.
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