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Highly diastereoselective synthesis of arylglycine derivatives via TFA-promoted Friedel-Crafts reactions of phenols with cyclic glyoxylate imines
Chen, YJ; Lei, F; Liu, L; Wang, D
2003-09-15
Source PublicationTETRAHEDRON
ISSN0040-4020
Volume59Issue:38Pages:7609-7614
AbstractOptically active alpha-arylglycine derivatives were synthesized by Bronsted acid (TFA)-promoted Friedel-Crafts reaction of various phenols with chiral cyclic glyoxylate imines (2a-c), followed by deprotection with Pd(OH)(2)/C under H-2. The diastereoselectivities of the initially formed F-C reaction products are up to 99%. (C) 2003 Elsevier Ltd. All rights reserved.
KeywordArylglycine F-c Reaction Phenol Chiral Cyclic Glyoxylate Imine Diastereoselective Synthesis
DOI10.1016/S0040-4020(03)01142-6
Indexed BySCI ; IC ; CCR
Language英语
WOS IDWOS:000186352100022
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:28[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/81252
Collection中国科学院化学研究所
Corresponding AuthorChen, YJ
AffiliationChinese Acad Sci, Ctr Mol Sci, Biol Chem Lab, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Chen, YJ,Lei, F,Liu, L,et al. Highly diastereoselective synthesis of arylglycine derivatives via TFA-promoted Friedel-Crafts reactions of phenols with cyclic glyoxylate imines[J]. TETRAHEDRON,2003,59(38):7609-7614.
APA Chen, YJ,Lei, F,Liu, L,&Wang, D.(2003).Highly diastereoselective synthesis of arylglycine derivatives via TFA-promoted Friedel-Crafts reactions of phenols with cyclic glyoxylate imines.TETRAHEDRON,59(38),7609-7614.
MLA Chen, YJ,et al."Highly diastereoselective synthesis of arylglycine derivatives via TFA-promoted Friedel-Crafts reactions of phenols with cyclic glyoxylate imines".TETRAHEDRON 59.38(2003):7609-7614.
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