ICCAS OpenIR
Synthesis of fused N-heterocycles utilizing the heterocyclic enamine protocol
Liu, Y; Yu, CY; Wang, MX
2003
Source PublicationARKIVOC
Pages146-154
AbstractHeterocyclic enamines 1 underwent regioselective C-benzylation and C-benzoylation with o-bromobenzyl bromide and o-halobenzoyl chloride to yield the corresponding C-benzylated and C-benzoylated heterocyclic enamines 2 and 8, respectively. Subsequent intramolecular substitution reactions of 2 and of 8 led to, respectively, the fused 1,4-dihydroquinolines 3 and quinolin-4-ones 9. The ring size effect of the heterocyclic enamines on the reactivity of both the enaminic carbon and the secondary amine was observed.
KeywordHeterocyclic Enamines Benzylation Benzoylation Fused Quinolin-4-ones Fused 1 4-dihydroquinolines
Indexed BySCI
Language英语
WOS IDWOS:000184637100017
PublisherARKAT USA INC
Citation statistics
Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/80442
Collection中国科学院化学研究所
Corresponding AuthorWang, MX
AffiliationChinese Acad Sci, Inst Chem, Ctr Mol Sci, Biol Chem Lab, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Liu, Y,Yu, CY,Wang, MX. Synthesis of fused N-heterocycles utilizing the heterocyclic enamine protocol[J]. ARKIVOC,2003:146-154.
APA Liu, Y,Yu, CY,&Wang, MX.(2003).Synthesis of fused N-heterocycles utilizing the heterocyclic enamine protocol.ARKIVOC,146-154.
MLA Liu, Y,et al."Synthesis of fused N-heterocycles utilizing the heterocyclic enamine protocol".ARKIVOC (2003):146-154.
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