ICCAS OpenIR
Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress
Wang, L; Osborne, PG; Yu, X; Shangguan, D; Zhao, R; Han, HW; Liu, GQ
2003-05-01
Source PublicationNEUROCHEMISTRY INTERNATIONAL
ISSN0197-0186
Volume42Issue:6Pages:465-470
AbstractDue to complex influence, such as utilization and permeability of arterial vessels to oxygen, there is a considerable difference of oxygen tension between extracellular fluid and perfusate usually used in microdialysis (30-60 Torr versus 145 Torr). Dialysate dopamine and monoamine metabolites-3,4-dihydroxyphenylacetic acid, homovanillic acid and 5-hydroxyindoleacetic acid were measured under different kinds of oxygen tension solutions (145, 72, 48 Torr). In the acute and anesthetized group, dopamine, 3,4-dihydroxyphenylacetic acid, 5-hydroxyindoleacetic acid and homovanillic acid increased 72, 93, 86 and 65%, respectively when changing the perfusate from 145 Torr to near physiological 48 Torr, while in chronic and conscious group, carried out 72 h after surgery, these compounds showed obscure increases (only homovanillic acid produced a significant change of 14%).
KeywordDopamine Oxygen Tension Hyperoxia Oxidative Stress
Indexed BySCI
Language英语
WOS IDWOS:000181510800004
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/80240
Collection中国科学院化学研究所
Corresponding AuthorLiu, GQ
AffiliationChinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Wang, L,Osborne, PG,Yu, X,et al. Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress[J]. NEUROCHEMISTRY INTERNATIONAL,2003,42(6):465-470.
APA Wang, L.,Osborne, PG.,Yu, X.,Shangguan, D.,Zhao, R.,...&Liu, GQ.(2003).Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress.NEUROCHEMISTRY INTERNATIONAL,42(6),465-470.
MLA Wang, L,et al."Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress".NEUROCHEMISTRY INTERNATIONAL 42.6(2003):465-470.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, L]'s Articles
[Osborne, PG]'s Articles
[Yu, X]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, L]'s Articles
[Osborne, PG]'s Articles
[Yu, X]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, L]'s Articles
[Osborne, PG]'s Articles
[Yu, X]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.