ICCAS OpenIR
The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ
Yang, LM; Xu, Z; Zhang, YF; Xu, YZ; Zhou, S; Zhang, NW; Li, QB; Liu, Z; Wang, LX; Zhou, WJ; Xu, DF; Song, ZF; Weng, SF; Wu, JG
2003-10-01
Source PublicationSPECTROSCOPY AND SPECTRAL ANALYSIS
ISSN1000-0593
Volume23Issue:5Pages:883-884
AbstractIn our previous study, we demonstrated that the malignant tissues of digestive system, including stomach, colon, esophagus, gallbladder etc., can be distinguished from the normal tissues using FT-Mid-IR methods. In the present investigation, we have been successful in realizing the detection of the tumor tissue of rectum in vivo and in situ. The consents of patients were obtained. This non-invasive measurement was performed during the operation process in Third Hospital, Peking University using a mid-IR Fiber Optics (Spectra-Tech Corporation) with WQF-500 FTIR Spectrometer of Beijing Second Optical Instrument Factory. Experimental results demonstrated that the spectral features of normal and malignant tissues with blood supplement are similar to those obtained from our previous in-vitro measurement. For example, the strong bands located near 1400 and 1100 cm(-1) in a tumor spectrum of patient s rectum, which were measured in vivo and in situ during operation, indicated the malignancy of the tumor. This recent result means that in-situ FTIR spectroscopic method with fiber optics can be developed as a non-invasive, rapid, accurate and in vivo technique for operating surgery.
KeywordMid-ir Fiber Optics Ftir Cancer In Vivo And In Situ
Indexed BySCI
Language英语
WOS IDWOS:000186376200016
PublisherBEIJING UNIV PRESS
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Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/79720
Collection中国科学院化学研究所
Corresponding AuthorYang, LM
Affiliation1.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, State Key Lab Rare Earth Mat Chem & Applicat, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 3, Beijing 100083, Peoples R China
3.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Yang, LM,Xu, Z,Zhang, YF,et al. The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS,2003,23(5):883-884.
APA Yang, LM.,Xu, Z.,Zhang, YF.,Xu, YZ.,Zhou, S.,...&Wu, JG.(2003).The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ.SPECTROSCOPY AND SPECTRAL ANALYSIS,23(5),883-884.
MLA Yang, LM,et al."The application of mid-IR fiber optics to diagnosis of colon cancer in vivo and in situ".SPECTROSCOPY AND SPECTRAL ANALYSIS 23.5(2003):883-884.
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