ICCAS OpenIR
Enhanced cell affinity of poly (D,L-lactide) by combining plasma treatment with collagen anchorage
Yang, J; Bei, JZ; Wang, SG
2002-06-01
Source PublicationBIOMATERIALS
ISSN0142-9612
Volume23Issue:12Pages:2607-2614
AbstractSurface properties of poly (D,L-lactide) (PDLLA) were modified by combining plasma treatment and collagen modification. The changes of surface properties were characterized by contact angles, surface energy, X-ray photoelectron spectra and scanning electron microscopy. The mouse 3T3 fibroblasts were used Lis model cells to evaluate the cell affinity of PDLLA before and after modification. Effects of different modification methods including plasma treatment, collagen coating and combining plasma treatment with collagen anchorage were investigated and compared. The results showed that the hydrophilicity and surface-free energy were improved and reduced, respectively, after each modification. Plasma pre-treatment could improve the roughness as it incorporated the polar groups and positively charged groups onto the sample Surface; so the plasma pre-treated surface would benefit in anchoring more collagen tightly. As a result, cell affinity of PDLLA modified by combining plasma treatment with collagen anchorage was greatly improved. The modified materials could endure rinsing by PBS, which would facilitate further application when the modified materials were used as cells scaffold in tissue engineering. (C) 2002 Published by Elsevier Science Ltd.
KeywordCell Affinity Plasma Treatment Collagen Cells Scaffold Tissue Engineering Poly (d L-lactide)
Indexed BySCI
Language英语
WOS IDWOS:000175547200020
PublisherELSEVIER SCI LTD
Citation statistics
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/79128
Collection中国科学院化学研究所
Corresponding AuthorWang, SG
AffiliationChinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Yang, J,Bei, JZ,Wang, SG. Enhanced cell affinity of poly (D,L-lactide) by combining plasma treatment with collagen anchorage[J]. BIOMATERIALS,2002,23(12):2607-2614.
APA Yang, J,Bei, JZ,&Wang, SG.(2002).Enhanced cell affinity of poly (D,L-lactide) by combining plasma treatment with collagen anchorage.BIOMATERIALS,23(12),2607-2614.
MLA Yang, J,et al."Enhanced cell affinity of poly (D,L-lactide) by combining plasma treatment with collagen anchorage".BIOMATERIALS 23.12(2002):2607-2614.
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