ICCAS OpenIR
The aza-ene or the Michael addition? Examination of an unusual substituent effect on the reaction of heterocyclic ketene aminals with ethyl propiolate
Zhao, MX; Wang, MX; Huang, ZT
2002-02-11
Source PublicationTETRAHEDRON
ISSN0040-4020
Volume58Issue:7Pages:1309-1316
AbstractHeterocyclic ketene aminals having at least one secondary amino group underwent the aza-ene reaction with ethyl propiolate under various conditions to yield the corresponding adducts, which were readily transformed into the delta-lactam fused heterocyclic products with or without the aid of sodium ethoxide in refluxing ethanol, while the ester- and cyano-substituted tertiary enediamines acted as the strong Michael donor to add to ethyl propiolate in a polar or a protic solvent. The unusual substituent effect on the reactivity and mechanism was discussed. (C) 2002 Elsevier Science Ltd. All rights reserved.
KeywordHeterocyclic Ketene Aminals Ethyl Propiolate Substituent Effect Addition Reaction
Indexed BySCI ; IC
Language英语
WOS IDWOS:000174339600008
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:37[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/78598
Collection中国科学院化学研究所
Corresponding AuthorHuang, ZT
AffiliationChinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Zhao, MX,Wang, MX,Huang, ZT. The aza-ene or the Michael addition? Examination of an unusual substituent effect on the reaction of heterocyclic ketene aminals with ethyl propiolate[J]. TETRAHEDRON,2002,58(7):1309-1316.
APA Zhao, MX,Wang, MX,&Huang, ZT.(2002).The aza-ene or the Michael addition? Examination of an unusual substituent effect on the reaction of heterocyclic ketene aminals with ethyl propiolate.TETRAHEDRON,58(7),1309-1316.
MLA Zhao, MX,et al."The aza-ene or the Michael addition? Examination of an unusual substituent effect on the reaction of heterocyclic ketene aminals with ethyl propiolate".TETRAHEDRON 58.7(2002):1309-1316.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhao, MX]'s Articles
[Wang, MX]'s Articles
[Huang, ZT]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhao, MX]'s Articles
[Wang, MX]'s Articles
[Huang, ZT]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhao, MX]'s Articles
[Wang, MX]'s Articles
[Huang, ZT]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.