ICCAS OpenIR
Annulation of heterocyclic secondary enamines with dicarboxylic acid dichlorides, an unexpected ring size effect
Cheng, Y; Yang, HB; Huang, ZT; Wang, MX
2001-02-26
Source PublicationTETRAHEDRON LETTERS
ISSN0040-4039
Volume42Issue:9Pages:1757-1759
AbstractUnder very mild conditions heterocyclic secondary enamines react efficiently with malonyl chloride to produce hydroxylated 2-pyridinone-fused heterocycles. The reactions of enamines with oxalyl chloride, however, afford varied products depending upon the heterocyclic structure of the enamine. Whilst a C-acylated enamine and a lactam-fused heterocycle were obtained from the reaction of the five- and seven-membered heterocyclic enamines, respectively, the six-membered heterocyclic enamine gave 2-oxo-5,6,7,8-tetrahydro-2H-pyrido[3,2-b]. The reaction mechanisms are discussed. (C) 2001 Elsevier Science Ltd. All rights reserved.
Indexed ByIC ; CCR ; SCI
Language英语
WOS IDWOS:000167205100042
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/78014
Collection中国科学院化学研究所
Corresponding AuthorCheng, Y
Affiliation1.Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China
2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Cheng, Y,Yang, HB,Huang, ZT,et al. Annulation of heterocyclic secondary enamines with dicarboxylic acid dichlorides, an unexpected ring size effect[J]. TETRAHEDRON LETTERS,2001,42(9):1757-1759.
APA Cheng, Y,Yang, HB,Huang, ZT,&Wang, MX.(2001).Annulation of heterocyclic secondary enamines with dicarboxylic acid dichlorides, an unexpected ring size effect.TETRAHEDRON LETTERS,42(9),1757-1759.
MLA Cheng, Y,et al."Annulation of heterocyclic secondary enamines with dicarboxylic acid dichlorides, an unexpected ring size effect".TETRAHEDRON LETTERS 42.9(2001):1757-1759.
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