ICCAS OpenIR
Enantioselective biotransformations of racemic 2-aryl-3-methylbutyronitriles using Rhodococcus sp AJ270
Wang, MX; Li, JJ; Ji, GJ; Li, JS
2001-07-06
Source PublicationJOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
ISSN1381-1177
Volume14Issue:4-6Pages:77-83
AbstractRhodococcus sp. AJ270 is a useful biocatalyst for the synthesis of some enantiopure S-(+)-2-aryl-3-methylbutyric acids and R-(+)-2-aryl-3-methylbutyramides from the hydrolysis of 2-aryl-3-methylbutyronitriles under mild conditions. The nitrile-hydrolyzing enzymes involved in this novel microorganism are very sensitive to the steric effect of the para-substituent on the aromatic ring. While the nitrile hydratase displays a low S-enantioselectivity against nitriles, the amidase has a strict S-enantioselectivity against 2-aryl-3-methylbutyramides. (C) 2001 Elsevier Science B.V. All rights reserved.
KeywordEnantioselective Biotransformations 2-aryl-3-methylbutyronitriles S-(+)-2-aryl-3-methylbutyric Acids R-(-)-2-aryl-3-methylbutyramides
Indexed BySCI
Language英语
WOS IDWOS:000169767400002
PublisherELSEVIER SCIENCE BV
Citation statistics
Cited Times:34[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/77932
Collection中国科学院化学研究所
Corresponding AuthorWang, MX
AffiliationChinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Wang, MX,Li, JJ,Ji, GJ,et al. Enantioselective biotransformations of racemic 2-aryl-3-methylbutyronitriles using Rhodococcus sp AJ270[J]. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC,2001,14(4-6):77-83.
APA Wang, MX,Li, JJ,Ji, GJ,&Li, JS.(2001).Enantioselective biotransformations of racemic 2-aryl-3-methylbutyronitriles using Rhodococcus sp AJ270.JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC,14(4-6),77-83.
MLA Wang, MX,et al."Enantioselective biotransformations of racemic 2-aryl-3-methylbutyronitriles using Rhodococcus sp AJ270".JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 14.4-6(2001):77-83.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, MX]'s Articles
[Li, JJ]'s Articles
[Ji, GJ]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, MX]'s Articles
[Li, JJ]'s Articles
[Ji, GJ]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, MX]'s Articles
[Li, JJ]'s Articles
[Ji, GJ]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.