ICCAS OpenIR
High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads
Zhao, YX; Shangguan, DH; Zhao, R; Shu, TS; Liu, GQ
2001-05-01
Source PublicationCHINESE CHEMICAL LETTERS
ISSN1001-8417
Volume12Issue:5Pages:443-446
AbstractA new approach for the separation of antithrombin III with high performance affinity chromatography (HPAC) was described. A novel monodisperse, non-porous, cross-linked poly (glycidyl methacrylate) beads (PGMA) were used as the affinity support. With the water-soluble carbodiimide, heparin was linked covalently to amino-PGMA-beads, which was prepared by amination of PGMA. The adsorbent obtained exhibits high binding activity to antithrombin III (ATIII), good resolution and excellent mechanical properties and can be used under high flow rate.
KeywordHigh Performance Affinity Chromatography Antithrombin Iii Heparin
Indexed BySCI
Language英语
WOS IDWOS:000168994500023
PublisherCHINESE CHEMICAL SOCIETY
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/77244
Collection中国科学院化学研究所
AffiliationChinese Acad Sci, Ctr Mol Sci, Inst Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Zhao, YX,Shangguan, DH,Zhao, R,et al. High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads[J]. CHINESE CHEMICAL LETTERS,2001,12(5):443-446.
APA Zhao, YX,Shangguan, DH,Zhao, R,Shu, TS,&Liu, GQ.(2001).High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads.CHINESE CHEMICAL LETTERS,12(5),443-446.
MLA Zhao, YX,et al."High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads".CHINESE CHEMICAL LETTERS 12.5(2001):443-446.
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