ICCAS OpenIR
Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds
Xu, SC; Zhang, HJ; Sun, ZY; Feng, J; Ai, XC; Zhang, QY; Zhang, XK; Liu, YQ; Han, ST
2001-10-01
Source PublicationACTA PHYSICO-CHIMICA SINICA
ISSN1000-6818
Volume17Issue:10Pages:879-886
Abstract5-fluorouracil porphyrin compounds are a new type of potential antitumor drugs. Six new 5-fluorouracil porphyrin compounds were synthesized first and characterized by means of elemental analysis, IR, (HNMR)-H-1 and MS. The six 5-fluorouracil porphyrin compounds were studied by absorption spectra, steady-state fluorescence spectroscopy and time-resolved single photon measurement, comparing with their primary porphyrin compounds. The 5-fluorouracil porphyrin compounds with plentiful excited states and fluorescence lifetime of 7 ns are little influenced by substituents and solvents, which may be advantageously used to make singlet oxygen radical.
Keyword5-fluorouracil Porphyrin Fluorescence Lifetime Single Photon Measurement
DOI10.3866/PKU.WHXB20011004
Indexed BySCI
Language英语
WOS IDWOS:000171639800004
PublisherPEKING UNIV PRESS
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/77098
Collection中国科学院化学研究所
Corresponding AuthorXu, SC
Affiliation1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100080, Peoples R China
2.Hebei Normal Univ, Dept Chem, Shijiazhuang 050091, Peoples R China
Recommended Citation
GB/T 7714
Xu, SC,Zhang, HJ,Sun, ZY,et al. Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds[J]. ACTA PHYSICO-CHIMICA SINICA,2001,17(10):879-886.
APA Xu, SC.,Zhang, HJ.,Sun, ZY.,Feng, J.,Ai, XC.,...&Han, ST.(2001).Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds.ACTA PHYSICO-CHIMICA SINICA,17(10),879-886.
MLA Xu, SC,et al."Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds".ACTA PHYSICO-CHIMICA SINICA 17.10(2001):879-886.
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