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Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds | |
Xu, SC; Zhang, HJ; Sun, ZY; Feng, J; Ai, XC; Zhang, QY; Zhang, XK; Liu, YQ; Han, ST | |
2001-10-01 | |
Source Publication | ACTA PHYSICO-CHIMICA SINICA
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ISSN | 1000-6818 |
Volume | 17Issue:10Pages:879-886 |
Abstract | 5-fluorouracil porphyrin compounds are a new type of potential antitumor drugs. Six new 5-fluorouracil porphyrin compounds were synthesized first and characterized by means of elemental analysis, IR, (HNMR)-H-1 and MS. The six 5-fluorouracil porphyrin compounds were studied by absorption spectra, steady-state fluorescence spectroscopy and time-resolved single photon measurement, comparing with their primary porphyrin compounds. The 5-fluorouracil porphyrin compounds with plentiful excited states and fluorescence lifetime of 7 ns are little influenced by substituents and solvents, which may be advantageously used to make singlet oxygen radical. |
Keyword | 5-fluorouracil Porphyrin Fluorescence Lifetime Single Photon Measurement |
DOI | 10.3866/PKU.WHXB20011004 |
Indexed By | SCI |
Language | 英语 |
WOS ID | WOS:000171639800004 |
Publisher | PEKING UNIV PRESS |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.iccas.ac.cn/handle/121111/77098 |
Collection | 中国科学院化学研究所 |
Corresponding Author | Xu, SC |
Affiliation | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100080, Peoples R China 2.Hebei Normal Univ, Dept Chem, Shijiazhuang 050091, Peoples R China |
Recommended Citation GB/T 7714 | Xu, SC,Zhang, HJ,Sun, ZY,et al. Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds[J]. ACTA PHYSICO-CHIMICA SINICA,2001,17(10):879-886. |
APA | Xu, SC.,Zhang, HJ.,Sun, ZY.,Feng, J.,Ai, XC.,...&Han, ST.(2001).Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds.ACTA PHYSICO-CHIMICA SINICA,17(10),879-886. |
MLA | Xu, SC,et al."Synthesis and spectroscopy characteristics of 5-fluorouracil porphyrin compounds".ACTA PHYSICO-CHIMICA SINICA 17.10(2001):879-886. |
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