ICCAS OpenIR
Branched nanowire based guanine rich oligonucleotides
Zhou, CQ; Tan, ZK; Wang, C; Wei, ZQ; Wang, ZG; Bai, CL; Qin, JF; Cao, EH
2001-06-01
Source PublicationJOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
ISSN0739-1102
Volume18Issue:6Pages:807-812
AbstractSelf-assembly and aggregation of guanine rich sequences can provide useful insights into DNA nanotechnology and telomeric structure and function. In this paper, we designed a guanine rich sequence d(GGCGTTTTGCGG). We found that it can form stable structure in appropriate condition and it exhibits an anomalous CD spectra. This structures can be imaged in ambient environment with a Nanoscope III AFM (Digital Instruments). We found it forms branch structure and long multistrand DNA nanowire after incubation at 37 degreesC for 6-12 hours in 25 mM TE (pH=8.0) + 5 mM Mg2+ + 50 mM K+. The ability to self-assemble into branches and long wires not only clearly demonstrate its potential as scaffold structures for nanotechnology, but also give aids to understand telomeric structure further. We have proposed a model to explain how these structures formed.
Indexed BySCI
Language英语
WOS IDWOS:000169439700002
PublisherADENINE PRESS INC
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/76988
Collection中国科学院化学研究所
Corresponding AuthorBai, CL
Affiliation1.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Inst Biophys, Beijing 100101, Peoples R China
Recommended Citation
GB/T 7714
Zhou, CQ,Tan, ZK,Wang, C,et al. Branched nanowire based guanine rich oligonucleotides[J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,2001,18(6):807-812.
APA Zhou, CQ.,Tan, ZK.,Wang, C.,Wei, ZQ.,Wang, ZG.,...&Cao, EH.(2001).Branched nanowire based guanine rich oligonucleotides.JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,18(6),807-812.
MLA Zhou, CQ,et al."Branched nanowire based guanine rich oligonucleotides".JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 18.6(2001):807-812.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhou, CQ]'s Articles
[Tan, ZK]'s Articles
[Wang, C]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhou, CQ]'s Articles
[Tan, ZK]'s Articles
[Wang, C]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhou, CQ]'s Articles
[Tan, ZK]'s Articles
[Wang, C]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.