ICCAS OpenIR
Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo
Ma, XY; Pan, GM; Lu, Z; Hu, JS; Bei, JZ; Jia, JH; Wang, SG
2000-07-01
Source PublicationDIABETES OBESITY & METABOLISM
ISSN1462-8902
Volume2Issue:4Pages:243-250
AbstractAim: Although the oral route for insulin delivery is the most convenient, directly administered oral insulin is degraded by proteolytic enzymes in the gastrointestinal (GI) tract. Polylactide was prepared in order to microcapsulate the insulin to avoid the enzymes in the GI. The physical characteristics and therapeutic possibilities of polylactide microcapsulated insulin (PLA-MCI) were studied in vivo and in vitro.
KeywordDiabetes Oral Insulin Microcapsulation Polylactide
Indexed BySCI
Language英语
WOS IDWOS:000088302800006
PublisherBLACKWELL SCIENCE LTD
Citation statistics
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/75884
Collection中国科学院化学研究所
Corresponding AuthorMa, XY
Affiliation1.Beijing 304 Hosp PLA, Dept Endocrinol, Beijing 1000037, Peoples R China
2.Chinese Acad Sci, Inst Chem, PCLCC, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Ma, XY,Pan, GM,Lu, Z,et al. Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo[J]. DIABETES OBESITY & METABOLISM,2000,2(4):243-250.
APA Ma, XY.,Pan, GM.,Lu, Z.,Hu, JS.,Bei, JZ.,...&Wang, SG.(2000).Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo.DIABETES OBESITY & METABOLISM,2(4),243-250.
MLA Ma, XY,et al."Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo".DIABETES OBESITY & METABOLISM 2.4(2000):243-250.
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