ICCAS OpenIR
Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os
Cheng, Y; Liu, MZ; Li, Y; Li, RC; Bai, CL; Wang, K
2000-03-01
Source PublicationCHINESE SCIENCE BULLETIN
ISSN1001-6538
Volume45Issue:5Pages:426-429
AbstractTo explore the possibility of absorption of lanthanides via digestive duct and their effects on the membrane structure and permeability of erythrocytes, the fine structure of erythrocyte membrane from Wistar rats, fed for 70 days of daily administration per os with 20 mg CeCl3/kg weight, was imaged by means of atomic force microscopy and FT-IR deconvolution spectra. The results show that, although the erythrocytes maintain the intact shape, the change of secondary structure, aggregation and crosslinking of the protein particles of membrane surface and the enlarged lipid regions lead to the domain structure formation. This structure might be responsible for the increasing permeability of erythrocyte membrane.
KeywordAfm Ft-ir Cecl3 Domain Structure Wistar Rat Erythrocyte
Indexed BySCI
Language英语
WOS IDWOS:000086025900010
PublisherSCIENCE PRESS
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/75772
Collection中国科学院化学研究所
Corresponding AuthorWang, K
Affiliation1.Beijing Med Univ, Nat Res Labs Nat Biomimetr, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Cheng, Y,Liu, MZ,Li, Y,et al. Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os[J]. CHINESE SCIENCE BULLETIN,2000,45(5):426-429.
APA Cheng, Y,Liu, MZ,Li, Y,Li, RC,Bai, CL,&Wang, K.(2000).Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os.CHINESE SCIENCE BULLETIN,45(5),426-429.
MLA Cheng, Y,et al."Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os".CHINESE SCIENCE BULLETIN 45.5(2000):426-429.
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