ICCAS OpenIR
Oxygen permeability of biodegradable copolycaprolactones
Wang, SG; Nishide, H; Tsuchida, E
1999-05-01
Source PublicationPOLYMERS FOR ADVANCED TECHNOLOGIES
ISSN1042-7147
Volume10Issue:5Pages:282-286
AbstractPolycaprolactone is one of the biodegradable polymers with good drug permeability. In the present paper, polycaprolactone and three kinds of copolycaprolactone-polycaprolactone-poly(ethylene oxide)-polycaprolactone triblock copolymer (PCE), polycaprolactone/polycaprolactone-poly(ethylene oxide)/polylactide tricomponents random block copolymer (PCEL) and polycaprolactone/poly(ethylene terephthalate) random block copolymer (PETCL)- were synthetized. The biodegradation behavior of these polymers were shown by degradation tests in vitro, ex vivo and in vivo. The oxygen permeabilities of these polymers were in the range of 10(-10) similar to 10(-9) cm(3) (STP) cm/cm(2) sec cm Hg. Copolymers PCE and PCEL displayed O-2 and N-2 permeability coefficients (PO2/PN2) ratios of about 9. The effects of composition and crystallinity of the copolymers on biodegradability and the oxygen permeability of the polymer were discussed. Copyright (C) 1999 John Wiley & Sons, Ltd.
KeywordPolycaprolactone Copolymer Biodegradability Oxygen Permeability
Indexed BySCI
Language英语
WOS IDWOS:000080509300006
PublisherJOHN WILEY & SONS LTD
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Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/75336
Collection中国科学院化学研究所
Corresponding AuthorTsuchida, E
Affiliation1.Waseda Univ, Dept Polymer Chem, Tokyo 1698555, Japan
2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Wang, SG,Nishide, H,Tsuchida, E. Oxygen permeability of biodegradable copolycaprolactones[J]. POLYMERS FOR ADVANCED TECHNOLOGIES,1999,10(5):282-286.
APA Wang, SG,Nishide, H,&Tsuchida, E.(1999).Oxygen permeability of biodegradable copolycaprolactones.POLYMERS FOR ADVANCED TECHNOLOGIES,10(5),282-286.
MLA Wang, SG,et al."Oxygen permeability of biodegradable copolycaprolactones".POLYMERS FOR ADVANCED TECHNOLOGIES 10.5(1999):282-286.
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