ICCAS OpenIR
Loop and water effect on stability of intertriplex DNA
Yang, LJ; Lee, IS; Wang, C; Li, Q; Bai, CL
1998-02-03
Source PublicationJOURNAL OF MOLECULAR STRUCTURE
ISSN0022-2860
Volume442Issue:1-3Pages:275-280
AbstractStability of four intratriplexes and one intertriplex influenced by loops and water have been investigated by molecular mechanics calculation. The four intratriplexes are 5'-d(TC)(6)-d(T)(m)-d(CT)(6)-d(C)(n)-d(AG)(6)-3' (m, n = 3 or 4), the corresponding intertripler is d(TC)(6)*d(AG)(6).d(CT)(6) (., Watson-Crick hydrogen bond; *, Hoogsteen hydrogen band). We studied in detail how loops and water would effect intra-and interstrand interactions of the five triplexes, respectively. The results showed that the existence of loops may have limited impact on the stability of the concerned triplex structures, regardless of water environment. In contrast, water molecules do have appreciable effects on tripler stability. Sugar conformations of the five triplexes were also discussed in this paper. The theoretical results are in good agreement with the FT-IR experiments. (C) 1998 Elsevier Science B.V.
KeywordIntertriplex Dna Stability Molecular Mechanics Loop Water
Indexed BySCI
Language英语
WOS IDWOS:000072445300030
PublisherELSEVIER SCIENCE BV
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/74780
Collection中国科学院化学研究所
Corresponding AuthorBai, CL
AffiliationChinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Yang, LJ,Lee, IS,Wang, C,et al. Loop and water effect on stability of intertriplex DNA[J]. JOURNAL OF MOLECULAR STRUCTURE,1998,442(1-3):275-280.
APA Yang, LJ,Lee, IS,Wang, C,Li, Q,&Bai, CL.(1998).Loop and water effect on stability of intertriplex DNA.JOURNAL OF MOLECULAR STRUCTURE,442(1-3),275-280.
MLA Yang, LJ,et al."Loop and water effect on stability of intertriplex DNA".JOURNAL OF MOLECULAR STRUCTURE 442.1-3(1998):275-280.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yang, LJ]'s Articles
[Lee, IS]'s Articles
[Wang, C]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yang, LJ]'s Articles
[Lee, IS]'s Articles
[Wang, C]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yang, LJ]'s Articles
[Lee, IS]'s Articles
[Wang, C]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.