ICCAS OpenIR
Inhibition of Bioelectrochemical Activities of Polyaniline Uricase Electrode by Theophylline
Kan Jinqing1; Qiao Yuedong1; Mu Shaolin1; Li Yongfang2
1997
Source PublicationACTA PHYSICO-CHIMICA SINICA
ISSN1000-6818
Volume13Issue:3Pages:236-241
AbstractThe effect of theophylline on the immobilized enzyme has been investigated using polyaniline uricase electrode. The activity of the immobilized uricase is markedly inhibited by theophylline. However, this is a reversible inhibition. In the presence of theophylline, the effect of pH on the response current of the enzyme electrode is different from that without theophylline; the response current of the enzyme electrode rapidly increase with increasing potential from 0.20-0.5V, and then increases slowly with further increasing potential. The activation energy of the enzyme-catalyzed reaction is 47.8kJ.mol(-1) in the presence of theophylline, which is much larger than that without theophylline (29.9kJ.mol(-1)). This indicates that the path of the enzyme-catalyzed reaction was changed by theophylline.
KeywordPolyaniline Uricase Theophylline Inhibition Activation Energy
DOI10.3866/PKU.WHXB19970310
Indexed BySCI
Language英语
WOS IDWOS:000207601300010
PublisherPEKING UNIV PRESS
Citation statistics
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/74100
Collection中国科学院化学研究所
Corresponding AuthorKan Jinqing
Affiliation1.Yangzhou Univ, Teachers Coll, Dept Chem, Yangzhou 225002, Peoples R China
2.Chinese Acad, Inst Chem, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Kan Jinqing,Qiao Yuedong,Mu Shaolin,et al. Inhibition of Bioelectrochemical Activities of Polyaniline Uricase Electrode by Theophylline[J]. ACTA PHYSICO-CHIMICA SINICA,1997,13(3):236-241.
APA Kan Jinqing,Qiao Yuedong,Mu Shaolin,&Li Yongfang.(1997).Inhibition of Bioelectrochemical Activities of Polyaniline Uricase Electrode by Theophylline.ACTA PHYSICO-CHIMICA SINICA,13(3),236-241.
MLA Kan Jinqing,et al."Inhibition of Bioelectrochemical Activities of Polyaniline Uricase Electrode by Theophylline".ACTA PHYSICO-CHIMICA SINICA 13.3(1997):236-241.
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