ICCAS OpenIR
Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid
Yan, Shifeng1; Yin, Jingbo1; Cui, Lei2; Yang, Yan1; Chen, Xuesi3
2011-08-01
Source PublicationCOLLOIDS AND SURFACES B-BIOINTERFACES
ISSN0927-7765
Volume86Issue:1Pages:218-224
AbstractBioactive PLLA/surface-grafted silica (g-SiO(2)) nanocomposite scaffolds were fabricated by solid-liquid phase separation method. And solid PLLA/g-SiO(2) nanocomposite films were prepared by solution casting method. A series of parallel tube-like morphology and internal ladder-like structure of PLLA/g-SiO(2) nanocomposite scaffolds were observed by SEM. The formation of bone-like apatite in the simulated body fluid (SBF) was characterized by XRD, IR, SEM, EDS and weight measurement. The silica incorporation favors the formation of apatite. The growth of apatite with immersion time is found on the surfaces of both the PLLA/g-SiO(2) nanocomposite scaffolds and the films. The potential mechanism is that silanol groups of g-SiO(2) in the nanocomposites serve as nucleation sites for the formation of bone-like apatite crystals. (C) 2011 Elsevier B.V. All rights reserved.
KeywordPoly(L-lactic Acid) Scaffold Apatite Nanocomposites
DOI10.1016/j.colsurfb.2011.04.004
Indexed BySCI
Language英语
WOS IDWOS:000291458100031
PublisherELSEVIER SCIENCE BV
Citation statistics
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/73686
Collection中国科学院化学研究所
Corresponding AuthorYin, Jingbo
Affiliation1.Shanghai Univ, Sch Mat Sci & Engn, Dept Polymer Mat, Shanghai 201800, Peoples R China
2.Natl Tissue Engn Ctr China, Shanghai 200233, Peoples R China
3.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
Recommended Citation
GB/T 7714
Yan, Shifeng,Yin, Jingbo,Cui, Lei,et al. Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2011,86(1):218-224.
APA Yan, Shifeng,Yin, Jingbo,Cui, Lei,Yang, Yan,&Chen, Xuesi.(2011).Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid.COLLOIDS AND SURFACES B-BIOINTERFACES,86(1),218-224.
MLA Yan, Shifeng,et al."Apatite-forming ability of bioactive poly(L-lactic acid)/grafted silica nanocomposites in simulated body fluid".COLLOIDS AND SURFACES B-BIOINTERFACES 86.1(2011):218-224.
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