ICCAS OpenIR
Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior
Yan, Shifeng1; Yin, Jingbo1; Tang, Li1; Chen, Xuesi2
2011-02-15
Source PublicationJOURNAL OF APPLIED POLYMER SCIENCE
ISSN0021-8995
Volume119Issue:4Pages:2350-2358
AbstractNovel hydrogels, physically crosslinked by hydrogen bonding of component polymers, were obtained by mixing aqueous solutions of carboxymethylchitosan (CMCS) with cellulose ethers including hydroxyethylcellulose (HEC) and methylcellulose (MC). The hydrogels were characterized by IR, XPS, WAXD, and SEM. The swelling and controlled drug release behaviors of hydrogels were also studied. The results indicate that intermacromolecular hydrogen bonding in CMCS/HEC is stronger than that in CMCS/MC. The swelling and drug release rate of hydrogels decrease as the interaction of component polymers increases. Both the swelling and drug release from hydrogels can be controlled by component polymer ratio. The hydrogels may be potential candidates for biomedical applications. VC 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 2350-2358, 2011
KeywordHydrogel Crosslinking Carboxymethylchitosan Hydroxyethylcellulose Methylcellulose
DOI10.1002/app.32678
Indexed BySCI
Language英语
WOS IDWOS:000284233500055
PublisherWILEY-BLACKWELL
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/72110
Collection中国科学院化学研究所
Corresponding AuthorYin, Jingbo
Affiliation1.Shanghai Univ, Sch Mat Sci & Engn, Dept Polymer Mat, Shanghai 201800, Peoples R China
2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
Recommended Citation
GB/T 7714
Yan, Shifeng,Yin, Jingbo,Tang, Li,et al. Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2011,119(4):2350-2358.
APA Yan, Shifeng,Yin, Jingbo,Tang, Li,&Chen, Xuesi.(2011).Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior.JOURNAL OF APPLIED POLYMER SCIENCE,119(4),2350-2358.
MLA Yan, Shifeng,et al."Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior".JOURNAL OF APPLIED POLYMER SCIENCE 119.4(2011):2350-2358.
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