ICCAS OpenIR
PH-responsive nano-assemblies of amino poly(glycerol methacrylate)
Gao Hui1; Ma Yanan1; Lu Xueyou1; Liang Yongri2; Chen Baoquan1; Ma Jianbiao1,3
2011-06-01
Source PublicationEUROPEAN POLYMER JOURNAL
ISSN0014-3057
Volume47Issue:6Pages:1232-1239
AbstractBoth linear and star-shaped poly(glycidyl methacrylate) (PGMA) polymers were modified with different amines and used to prepare pH-sensitive nano-assemblies. Nanoprecipitation technique and dialysis method were used to prepare the polymeric nanoparticles. These nano-assemblies showed pH-sensitive disassociation properties under an acidic condition. The polymers were quite effective in encapsulation of Congo red (CR). Atom force microscopy images showed that the nanoparticles prepared using nanoprecipitation technique are spherical before and after encapsulation of CR. The disassociation pH, encapsulation efficiency, loading capacity and release properties of these polymers were found to depend on their backbone architecture and the amine type. By adjusting of these factors, such type of polymers hold promise as an interesting drug delivery vehicle. (C) 2011 Elsevier Ltd. All rights reserved.
KeywordPh-sensitive Nanoparticles Amino Polymer Poly(Glycidyl Methacrylate) Congo Red
DOI10.1016/j.eurpolymj.2011.03.009
Indexed BySCI
Language英语
WOS IDWOS:000291523600002
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/72022
Collection中国科学院化学研究所
Corresponding AuthorGao Hui
Affiliation1.Tianjin Univ Technol, Sch Chem & Chem Engn, Tianjin 300384, Peoples R China
2.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
3.Nankai Univ, Inst Polymer Chem, Minist Educ, Key Lab Funct Polymer Mat, Tianjin 300071, Peoples R China
Recommended Citation
GB/T 7714
Gao Hui,Ma Yanan,Lu Xueyou,et al. PH-responsive nano-assemblies of amino poly(glycerol methacrylate)[J]. EUROPEAN POLYMER JOURNAL,2011,47(6):1232-1239.
APA Gao Hui,Ma Yanan,Lu Xueyou,Liang Yongri,Chen Baoquan,&Ma Jianbiao.(2011).PH-responsive nano-assemblies of amino poly(glycerol methacrylate).EUROPEAN POLYMER JOURNAL,47(6),1232-1239.
MLA Gao Hui,et al."PH-responsive nano-assemblies of amino poly(glycerol methacrylate)".EUROPEAN POLYMER JOURNAL 47.6(2011):1232-1239.
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