ICCAS OpenIR
Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy
Liu, Ningning1; Peng, Bo2; Lin, Yuan2,3,4; Su, Zhaohui2; Niu, Zhongwei3,4; Wang, Qian3,4; Zhang, Wenke1; Li, Hongbin5; Shen, Jiacong1
2010-08-18
Source PublicationJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
ISSN0002-7863
Volume132Issue:32Pages:11036-11038
AbstractRNA-coat protein interactions in intact tobacco mosaic virus have been investigated for the first time directly on the single-molecule level by pulling the genetic RNA step by step out of the helical groove formed by its protein coat. The effects of pulling speed and pH on RNA-protein interactions are presented. In addition, the rebinding behavior of the detached RNA with the protein coat is discussed. Our results demonstrate the possibility of studying nucleic acid-protein interactions in more complicated systems using AFM-based single-molecule force spectroscopy.
DOI10.1021/ja1052544
Indexed BySCI
Language英语
WOS IDWOS:000280861300031
PublisherAMER CHEMICAL SOC
Citation statistics
Cited Times:51[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/71196
Collection中国科学院化学研究所
Corresponding AuthorZhang, Wenke
Affiliation1.Jilin Univ, State Key Lab Supramol Struct & Mat, Coll Chem, Changchun 130012, Peoples R China
2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
3.Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA
4.Univ S Carolina, NanoCtr, Columbia, SC 29208 USA
5.Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada
Recommended Citation
GB/T 7714
Liu, Ningning,Peng, Bo,Lin, Yuan,et al. Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2010,132(32):11036-11038.
APA Liu, Ningning.,Peng, Bo.,Lin, Yuan.,Su, Zhaohui.,Niu, Zhongwei.,...&Shen, Jiacong.(2010).Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,132(32),11036-11038.
MLA Liu, Ningning,et al."Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 132.32(2010):11036-11038.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu, Ningning]'s Articles
[Peng, Bo]'s Articles
[Lin, Yuan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu, Ningning]'s Articles
[Peng, Bo]'s Articles
[Lin, Yuan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu, Ningning]'s Articles
[Peng, Bo]'s Articles
[Lin, Yuan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.