ICCAS OpenIR
Principle and Applications of Scanning Ion Conductance Microscopy
Ji Tian-Rong; Liang Zhong-Wei; Zhu Xin-Yu; Shao Yuan-Hua
2010-12-01
Source PublicationCHINESE JOURNAL OF ANALYTICAL CHEMISTRY
ISSN0253-3820
Volume38Issue:12Pages:1821-1827
AbstractScanning ion conductance microscopy (SICM) is one type of scanning probe microscopy (SPM) techniques. By measuring the ionic current of an ultra-micropipette, it can be used to map the surface topography of a sample at high resolution without any contact. SICM has many remarkable advantages, such as high spatial resolution, simple preparation of the probe and no damage to the sample surface, particularly suitable for imaging living cells under physiological condition. Therefore, SICM is an important scanning probe microscopy technique complementary to scanning electrochemical microscopy and atomic force microscopy. SICM has been employed to image soft interfaces and surfaces, such as cell surface and its microstructure. In addition, SICM can be used in conjunction with other techniques to study the relationship between cell topography and function; it can also control the deposition of specific molecules to achieve nanometer-scale microscopic operation and fabrication. Herein, the history, principle, instrumentation, applications and prospects of SICM have been reviewed.
KeywordScanning Ion Conductance Microscopy Principle Applications Review
DOI10.3724/SP.J.1096.2010.01821
Indexed BySCI
Language英语
WOS IDWOS:000287782500028
PublisherELSEVIER SCIENCE INC
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/70768
Collection中国科学院化学研究所
Corresponding AuthorJi Tian-Rong
AffiliationPeking Univ, Coll Chem & Mol Engn, Inst Analyt Chem, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Ji Tian-Rong,Liang Zhong-Wei,Zhu Xin-Yu,et al. Principle and Applications of Scanning Ion Conductance Microscopy[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2010,38(12):1821-1827.
APA Ji Tian-Rong,Liang Zhong-Wei,Zhu Xin-Yu,&Shao Yuan-Hua.(2010).Principle and Applications of Scanning Ion Conductance Microscopy.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,38(12),1821-1827.
MLA Ji Tian-Rong,et al."Principle and Applications of Scanning Ion Conductance Microscopy".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 38.12(2010):1821-1827.
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