ICCAS OpenIR
Fabrication of color changeable polystyrene spheres decorated by gold nanoparticles and their label-free biosensing
Xia, Yuetong; Lu, Wensheng; Jiang, Long
2010-02-26
Source PublicationNANOTECHNOLOGY
ISSN0957-4484
Volume21Issue:8
AbstractA novel and simple method for gold nanoshell synthesis with controllable core and shell sizes is reported here. A new 'tree-shape' surfactant bis(amidoethyl-carbamoylethyl) octadecylamine (C18N3) was synthesized and used as the glue for the fast combination of gold nanoparticles and the subsequent gold shell outside. The functionalized polystyrene (PS) cores were covered by a surfactant (PS@C18N3) bilayer. The presence of the surfactant double layer played the role of 'glue' in this method, so that upon controlling the amount of surfactant, it was possible to achieve: the manipulation of gold seed density on the PS@C18N3 spheres, the preparation of PS@Au hybrid structures, and a red-shift in the extinction absorption from 520 to 750 nm. Besides, the as-prepared PS@Au composites supported on a glass substrate exhibited excellent effectiveness in the molecular recognition of human-immunoglobulin G (h-IgG) and goat anti-human-immunoglobulin G (goat anti-h-IgG), showing a rapid response within 20 min with a low detection limit of 10 ng ml(-1). This demonstrates that PS@Au prepared and assembled using our method is potentially useful as a nanosensor platform for immunoassay.
DOI10.1088/0957-4484/21/8/085501
Indexed BySCI
Language英语
WOS IDWOS:000273965000008
PublisherIOP PUBLISHING LTD
Citation statistics
Cited Times:17[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/69588
Collection中国科学院化学研究所
Corresponding AuthorJiang, Long
AffiliationChinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Xia, Yuetong,Lu, Wensheng,Jiang, Long. Fabrication of color changeable polystyrene spheres decorated by gold nanoparticles and their label-free biosensing[J]. NANOTECHNOLOGY,2010,21(8).
APA Xia, Yuetong,Lu, Wensheng,&Jiang, Long.(2010).Fabrication of color changeable polystyrene spheres decorated by gold nanoparticles and their label-free biosensing.NANOTECHNOLOGY,21(8).
MLA Xia, Yuetong,et al."Fabrication of color changeable polystyrene spheres decorated by gold nanoparticles and their label-free biosensing".NANOTECHNOLOGY 21.8(2010).
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