ICCAS OpenIR
Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake
Sun, Xin; Chu, Taiwei; Wang, Xiangyun
2010-02-01
Source PublicationNUCLEAR MEDICINE AND BIOLOGY
ISSN0969-8051
Volume37Issue:2Pages:117-123
AbstractIntroduction: Tc-99m-BnAO is one of the nonnitroimidazole hypoxia markers with the highest citation and could be potentially useful in both oncology and other clinical applications. However, it appears inferior in vitro due to lower absolute accumulation and smaller anoxic/normoxic uptake ratio. It is possible that the analogues of Tc-99m-BnAO have higher hypoxia selectivity after the ligand of Tc-99m-BnAO is modified.
KeywordBnao Labeling Technetium-99m Hypoxia Marker Lipophilicity Cellular Accumulation
DOI10.1016/j.nucmedbio.2009.09.003
Indexed BySCI
Language英语
WOS IDWOS:000274947300002
PublisherELSEVIER SCIENCE INC
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/68750
Collection中国科学院化学研究所
Corresponding AuthorChu, Taiwei
AffiliationPeking Univ, Coll Chem & Mol Engn, Dept Appl Chem, BNLMS, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Sun, Xin,Chu, Taiwei,Wang, Xiangyun. Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake[J]. NUCLEAR MEDICINE AND BIOLOGY,2010,37(2):117-123.
APA Sun, Xin,Chu, Taiwei,&Wang, Xiangyun.(2010).Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake.NUCLEAR MEDICINE AND BIOLOGY,37(2),117-123.
MLA Sun, Xin,et al."Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake".NUCLEAR MEDICINE AND BIOLOGY 37.2(2010):117-123.
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