Knowledge Management System Of Institute of Chemistry,CAS
Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan | |
Gu JiangYong1; Yuan Gu1; Zhu YongHong2; Xu XiaoJie1 | |
2009-11-01 | |
Source Publication | SCIENCE IN CHINA SERIES B-CHEMISTRY
![]() |
ISSN | 1006-9291 |
Volume | 52Issue:11Pages:1871-1878 |
Abstract | Computational pharmacological methods were used to study the distribution of 1729 compounds contained in a Chinese medicine, Qishen Yiqi Diwan, in chemical space. The results show that most of these compounds have good drug-like properties. Molecular docking was used to study the interactions between 1729 compounds of Qishen Yiqi Diwan and 26 drug targets related to cardiovascular disease and the distribution of 1729 compounds in drug-target space. The results may shed light on the action mechanism and the search for the active compounds in Qishen Yiqi Diwan. |
Keyword | Chemical Space Drug-target Space Molecular Docking Computational Pharmacology |
DOI | 10.1007/s11426-009-0274-x |
Indexed By | SCI |
Language | 英语 |
WOS ID | WOS:000272032700019 |
Publisher | SCIENCE PRESS |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.iccas.ac.cn/handle/121111/68638 |
Collection | 中国科学院化学研究所 |
Corresponding Author | Xu XiaoJie |
Affiliation | 1.Peking Univ, Coll Chem & Mol Engn, State Key Lab Rare Earth Mat Chem & Applicat, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China 2.Acad Tasly Pharmaceut Co LTD, Tianjin 300410, Peoples R China |
Recommended Citation GB/T 7714 | Gu JiangYong,Yuan Gu,Zhu YongHong,et al. Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2009,52(11):1871-1878. |
APA | Gu JiangYong,Yuan Gu,Zhu YongHong,&Xu XiaoJie.(2009).Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan.SCIENCE IN CHINA SERIES B-CHEMISTRY,52(11),1871-1878. |
MLA | Gu JiangYong,et al."Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan".SCIENCE IN CHINA SERIES B-CHEMISTRY 52.11(2009):1871-1878. |
Files in This Item: | There are no files associated with this item. |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment