ICCAS OpenIR
Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors
Li, Bingling; Qin, Chuanjiang; Li, Tao; Wang, Lixiang1; Dong, Shaojun
2009-05-01
Source PublicationANALYTICAL CHEMISTRY
ISSN0003-2700
Volume81Issue:9Pages:3544-3550
AbstractHere, a fluorescent switch is constructed combining hemin, hemin aptamer, and a newly synthesized anionic conjugated polymer (ACP), poly(9,9-bis(6'-phosphate-hexyl) fluorenealt-1,4-phenylene) sodium salt (PFHPNa/PFP). In the "off-state", the fluorescence of PFP is sensitively quenched by hemin, with a high K(sv) value of similar to 10(7). While in the "on-state", the formation of the aptamer/hemin complex recovers the fluorescence intensity. The fluorescent switch is sensitive and selective to hemin. To testify the universality and practicality of the fluorescent switch, a series of label-free DNA-related sensing platforms are developed, containing three DNA sensing strategies and one ATP recognition strategy. The fluorescent switch developed is simple, sensitive, and universal, which extends applications of the anionic conjugated polymers.
DOI10.1021/ac900110a
Indexed BySCI
Language英语
WOS IDWOS:000265632400047
PublisherAMER CHEMICAL SOC
Citation statistics
Cited Times:29[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/67974
Collection中国科学院化学研究所
Corresponding AuthorWang, Lixiang
Affiliation1.Chinese Acad Sci, Changchun Inst Appl Chem, Grad Sch, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China
2.Chinese Acad Sci, Changchun Inst Appl Chem, Grad Sch, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
Recommended Citation
GB/T 7714
Li, Bingling,Qin, Chuanjiang,Li, Tao,et al. Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors[J]. ANALYTICAL CHEMISTRY,2009,81(9):3544-3550.
APA Li, Bingling,Qin, Chuanjiang,Li, Tao,Wang, Lixiang,&Dong, Shaojun.(2009).Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors.ANALYTICAL CHEMISTRY,81(9),3544-3550.
MLA Li, Bingling,et al."Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors".ANALYTICAL CHEMISTRY 81.9(2009):3544-3550.
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