ICCAS OpenIR
Visual observation of G-quadruplex DNA with the label-free fluorescent probe silole with aggregation-induced emission
Huang, Jing1; Wang, Ming2; Zhou, Yangyang1; Weng, Xiaocheng1; Shuai, Liang1; Zhou, Xiang1; Zhang, Deqing2
2009-11-15
Source PublicationBIOORGANIC & MEDICINAL CHEMISTRY
ISSN0968-0896
Volume17Issue:22Pages:7743-7748
AbstractAIE molecule silole 1 could be used to detect G-quadruplex formation using an exonuclease I hydrolysis assay. This visual observation of G-quadruplexes has been successfully used in investigating multiple G-quadruplexes, including the one-stranded telomeric, c-myc, c-kit, VEGF G-quadruplexes, and a d(G(4)T(4)G(4)) inter-molecular G-quadruplex. The detection of G-quadruplex can be also applied to G-quadruplex isomers induced by small molecules. (C) 2009 Elsevier Ltd. All rights reserved.
KeywordAie Silole G-quadruplex Visual Observation
DOI10.1016/j.bmc.2009.09.040
Indexed BySCI
Language英语
WOS IDWOS:000271340000013
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:21[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/67834
Collection中国科学院化学研究所
Corresponding AuthorZhou, Xiang
Affiliation1.Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China
2.Chinese Acad Sci, Grad Sch, Inst Chem, Beijing Natl Lab Mol Sci,Organ Solids Lab, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Huang, Jing,Wang, Ming,Zhou, Yangyang,et al. Visual observation of G-quadruplex DNA with the label-free fluorescent probe silole with aggregation-induced emission[J]. BIOORGANIC & MEDICINAL CHEMISTRY,2009,17(22):7743-7748.
APA Huang, Jing.,Wang, Ming.,Zhou, Yangyang.,Weng, Xiaocheng.,Shuai, Liang.,...&Zhang, Deqing.(2009).Visual observation of G-quadruplex DNA with the label-free fluorescent probe silole with aggregation-induced emission.BIOORGANIC & MEDICINAL CHEMISTRY,17(22),7743-7748.
MLA Huang, Jing,et al."Visual observation of G-quadruplex DNA with the label-free fluorescent probe silole with aggregation-induced emission".BIOORGANIC & MEDICINAL CHEMISTRY 17.22(2009):7743-7748.
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