ICCAS OpenIR
Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm
Sun, Jing1,2; Chen, Xuesi1; Guo, Jinshan1,2; Shi, Quan1,2; Xie, Zhigang1,2; Jing, Xiabin1
2009-01-16
Source PublicationPOLYMER
ISSN0032-3861
Volume50Issue:2Pages:455-461
AbstractA novel biodegradable Y-shaped copolymer, poly(L-lactide)(2)-b-poly(gamma-benzyl-L-glutamic acid) (PLLA(2)-b-PBLG), was synthesized by the ring-opening polymerization (ROP) of N-carboxyanhydride of gamma-benzyl-L-glutamate (BLG-NCA) with centrally amino-functionalized poly(L-lactide), PLLA(2)-NH(2), as a macroinitiator in a convenient way. The Y-shaped copolymer and its precursors were characterized by (1)H NMR, FT-IR, GPC, WAXD and DSC measurements. The self-assembly of the PLLA(2)-b-PBLG copolymer in toluene and benzyl alcohol was examined. It was found that the self-assembly of the copolymer was dependent on solvent and on relative length of the PBLG block. For a copolymer with PLLA blocks of 26 in total degree of polymerization (DP), if the PBLG block was long enough (e.g., DP = 54 or more), the copolymer/toluene solution became a transparent gel at room temperature. In benzyl alcohol Solution, only PLLA(2)-b-PBLG containing ca. 190 BLG residues could form a gel: those with shorter PBLG blocks (e.g., DP = 54) became nano-scale fibrous aggregates and these aggregates were dispersed in benzyl alcohol homogeneously. Copolymers with short PBLG blocks behaved like a pure PLLA both in toluene and in benzyl alcohol. These experimental results were discussed and explained by virtue of the helical conformation of PBLG and the interactions between the solvents and the PLLA and/or PBLG segments. (C) 2008 Elsevier Ltd. All rights reserved.
KeywordBiodegradable Nca Ring-opening Polymerization
DOI10.1016/j.polymer.2008.11.015
Indexed BySCI
Language英语
WOS IDWOS:000262592400015
PublisherELSEVIER SCI LTD
Citation statistics
Cited Times:31[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/67754
Collection中国科学院化学研究所
Corresponding AuthorJing, Xiabin
Affiliation1.Chinese Acad Sci, State Key Lab Polymer Phys & Chem, Changchun Inst Appl Chem, Changchun 130022, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Sun, Jing,Chen, Xuesi,Guo, Jinshan,et al. Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm[J]. POLYMER,2009,50(2):455-461.
APA Sun, Jing,Chen, Xuesi,Guo, Jinshan,Shi, Quan,Xie, Zhigang,&Jing, Xiabin.(2009).Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm.POLYMER,50(2),455-461.
MLA Sun, Jing,et al."Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm".POLYMER 50.2(2009):455-461.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Sun, Jing]'s Articles
[Chen, Xuesi]'s Articles
[Guo, Jinshan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Sun, Jing]'s Articles
[Chen, Xuesi]'s Articles
[Guo, Jinshan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Sun, Jing]'s Articles
[Chen, Xuesi]'s Articles
[Guo, Jinshan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.