ICCAS OpenIR
Label-free optical biosensors based on Au2S-coated gold nanorods
Huang, Haowen1; Huang, Shaowen1; Liu, Xuanyong2; Zeng, Yunlong1; Yu, Xianyong1; Liao, Bo1; Chen, Yi3
2009-06-15
Source PublicationBIOSENSORS & BIOELECTRONICS
ISSN0956-5663
Volume24Issue:10Pages:3025-3029
AbstractIn this research. two new types of optical biosensors were explored from Au2S-coated gold nanorods (Au2S-coated GNRs) chemically attached with human IgG as recognizing probes. The first type of biosensors were suspended GNRs and exhibited sensitive shift of longitudinal plasmon wavelength in response to anti-human IgG, with the limit of detection down to 67 pm. The second type of sensors were on-chip-immobilized GNRs, able to be used repeatedly through measuring the change of plasmon absorption intensity at a fixed wavelength, with the limit of detection down to 33 pM. The latter sensors suited for dynamic measurements, having linear response over rang from 33 pM to 1.35 nM. Both the types of sensors not only preserved the desirable features of common GNR sensors but also easy for preparation and manipulation. The concept and methodology suggested in this Study can serve as the basis to develop new methods for molecular binding events or other applications like in medical researches. (C) 2009 Elsevier B.V. All rights reserved.
KeywordLocalized Surface Plasmon Resonance Label-free Core-shell Structure Au2s-coated Gold Nanorods Biosensor
DOI10.1016/j.bios.2009.03.018
Indexed BySCI
Language英语
WOS IDWOS:000267162200013
PublisherELSEVIER ADVANCED TECHNOLOGY
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/67576
Collection中国科学院化学研究所
Corresponding AuthorHuang, Haowen
Affiliation1.Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Ceram, Shanghai 200050, Peoples R China
3.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Huang, Haowen,Huang, Shaowen,Liu, Xuanyong,et al. Label-free optical biosensors based on Au2S-coated gold nanorods[J]. BIOSENSORS & BIOELECTRONICS,2009,24(10):3025-3029.
APA Huang, Haowen.,Huang, Shaowen.,Liu, Xuanyong.,Zeng, Yunlong.,Yu, Xianyong.,...&Chen, Yi.(2009).Label-free optical biosensors based on Au2S-coated gold nanorods.BIOSENSORS & BIOELECTRONICS,24(10),3025-3029.
MLA Huang, Haowen,et al."Label-free optical biosensors based on Au2S-coated gold nanorods".BIOSENSORS & BIOELECTRONICS 24.10(2009):3025-3029.
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