A Simple Synthesis of Imide-Dipeptides
Ke, Damei1,2; Zhan, Chuanlang1; Li, Xiao1,2; Li, Alexander D. Q.3; Yao, Jiannian1
Source PublicationSYNLETT
AbstractWe report a simple approach to synthesize a new class of imide-dipeptides. This approach is mild, and the starting materials are the easily accessible amino acid derivatives. The imide-dipeptides were synthesized from the coupling of an amide and a 4-nitrophenyl activating ester of an amino acid. The acidic proton of the first amide was removed by 1 equivalent of n-butyl lithium to afford the corresponding amide anion which then reacted with the activating ester to give he desired imide derivatives.
KeywordImides Dipeptides Amino Acids Amides Coupling
Indexed BySCI ; IC
WOS IDWOS:000267168600032
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Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorZhan, Chuanlang
Affiliation1.Chinese Acad Sci, BNLMS, Lab Photochem, Inst Chem, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Washington State Univ, Dept Chem, Pullman, WA 99164 USA
Recommended Citation
GB/T 7714
Ke, Damei,Zhan, Chuanlang,Li, Xiao,et al. A Simple Synthesis of Imide-Dipeptides[J]. SYNLETT,2009(9):1506-1510.
APA Ke, Damei,Zhan, Chuanlang,Li, Xiao,Li, Alexander D. Q.,&Yao, Jiannian.(2009).A Simple Synthesis of Imide-Dipeptides.SYNLETT(9),1506-1510.
MLA Ke, Damei,et al."A Simple Synthesis of Imide-Dipeptides".SYNLETT .9(2009):1506-1510.
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