ICCAS OpenIR
Preparation of bioactive glass ceramic nanoparticles by combination of sol-gel and coprecipitation method
Hong, Zhongkui; Liu, Aixue; Chen, Li; Chen, Xuesi1; Jing, Xiabin
2009-03-01
Source PublicationJOURNAL OF NON-CRYSTALLINE SOLIDS
ISSN0022-3093
Volume355Issue:6Pages:368-372
AbstractSiO(2)-CaO-P(2)O(5) ternary bioactive glass ceramic nanoparticles were prepared via the combination of sol-gel and coprecipitation processes. Precursors of silicon and calcium were hydrolyzed in acidic solution and gelated in alkaline condition together with ammonium dibasic phosphate. Gel particles were separated by centrifugation, followed by freeze drying, and calcination procedure to obtain the bioactive glass ceramic nanoparticles. The investigation of the influence of synthesis temperature on the nanopartilce's properties showed that the reaction temperature played an important role in the crystallinity of nanoparticle. The glass ceramic particles synthesized at 55 degrees C included about 15% crystalline phase, while at 25 degrees C and 40 degrees C the entire amorphous nanopowder could be obtained. In vitro testing showed that the bioactive glass ceramic nanoparticles can induce the formation of hydroxylaptite from simulated body fluid rapidly. As a result, this bioactive glass ceramic nanoparticle with excellent bioactivity would be a promising filler material for bone tissues engineering. (C) 2008 Elsevier B.V. All rights reserved.
KeywordBioglass Biomaterials Ceramics Glass Ceramics Nanoparticles
DOI10.1016/j.jnoncrysol.2008.12.003
Indexed BySCI
Language英语
WOS IDWOS:000264595400006
PublisherELSEVIER SCIENCE BV
Citation statistics
Cited Times:62[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/66938
Collection中国科学院化学研究所
Corresponding AuthorChen, Xuesi
Affiliation1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Hong, Zhongkui,Liu, Aixue,Chen, Li,et al. Preparation of bioactive glass ceramic nanoparticles by combination of sol-gel and coprecipitation method[J]. JOURNAL OF NON-CRYSTALLINE SOLIDS,2009,355(6):368-372.
APA Hong, Zhongkui,Liu, Aixue,Chen, Li,Chen, Xuesi,&Jing, Xiabin.(2009).Preparation of bioactive glass ceramic nanoparticles by combination of sol-gel and coprecipitation method.JOURNAL OF NON-CRYSTALLINE SOLIDS,355(6),368-372.
MLA Hong, Zhongkui,et al."Preparation of bioactive glass ceramic nanoparticles by combination of sol-gel and coprecipitation method".JOURNAL OF NON-CRYSTALLINE SOLIDS 355.6(2009):368-372.
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