ICCAS OpenIR
Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes
Wang, X.1; Jia, G.1; Wang, H.2; Nie, H.2; Yan, L.1; Deng, X. Y.3; Wang, S.1
2009-05-01
Source PublicationJOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
ISSN1533-4880
Volume9Issue:5Pages:3025-3033
AbstractIn this work, we focus on the diameter effects on cytotoxicity of different diametered multi-walled carbon nanotubes (MWNTs). Cellular viability, phagocytotic ability, and apoptosis of guinea pig alveolar macrophages (AM) exposed to MWNTs were studied. MWNTs in smaller diameter showed less cytotoxicity than the larger ones at the same dosage. The phagocytosis ability of AM was partially impaired when the concentration of MWNTs was up to 20 mu g/ml, where a further characteristic feature of AM apoptosis was observed. The results indicate that MWNTs in different diameters exhibited quite different cytotoxicity, and for the first time revealed the diameter-effect of MWNTs on cytotoxicity.
KeywordCytotoxicity Alveolar Macrophages (Am) Diameter-effect Apoptosis Multi-walled Carbon Nanotubes (Mwnts)
DOI10.1166/jnn.2009.025
Indexed BySCI
Language英语
WOS IDWOS:000265186800033
PublisherAMER SCIENTIFIC PUBLISHERS
Citation statistics
Cited Times:62[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/66810
Collection中国科学院化学研究所
Corresponding AuthorJia, G.
Affiliation1.Peking Univ, Sch Publ Hlth, Dept Environm & Occupat Hlth, Beijing 100191, Peoples R China
2.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
3.Shanghai Univ, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China
Recommended Citation
GB/T 7714
Wang, X.,Jia, G.,Wang, H.,et al. Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2009,9(5):3025-3033.
APA Wang, X..,Jia, G..,Wang, H..,Nie, H..,Yan, L..,...&Wang, S..(2009).Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,9(5),3025-3033.
MLA Wang, X.,et al."Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 9.5(2009):3025-3033.
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