ICCAS OpenIR
Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice
Yang, Sheng-Tao1; Wang, Haifang1,2; Meziani, Mohammed J.3,4; Liu, Yuanfang1,2; Wang, Xin3,4; Sun, Ya-Ping3,4
2009-07-01
Source PublicationBIOMACROMOLECULES
ISSN1525-7797
Volume10Issue:7Pages:2009-2012
AbstractChemically modified carbon nanotubes with hydrophilic functionalities such as polyethylene glycols (PEGs) are widely pursued for potential biological and biomedical applications. In this study, PEGylated single-walled carbon nanotubes (PEG-SWNT) were intravenously administrated into mice to study their biodefunctionalization in vivo by using complementary Raman and photoluminescence measurements. There was meaningful defunctionalization of PEG-SWNT in liver over time, but not in spleen under similar conditions. The evidence from spectroscopic characterization and analyses is presented, and mechanistic implications are discussed.
DOI10.1021/bm900263z
Indexed BySCI
Language英语
WOS IDWOS:000268139300043
PublisherAMER CHEMICAL SOC
Citation statistics
Cited Times:35[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/66724
Collection中国科学院化学研究所
Corresponding AuthorWang, Haifang
Affiliation1.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
2.Shanghai Univ, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China
3.Clemson Univ, Dept Chem, Clemson, SC 29634 USA
4.Clemson Univ, Lab Emerging Mat & Technol, Clemson, SC 29634 USA
Recommended Citation
GB/T 7714
Yang, Sheng-Tao,Wang, Haifang,Meziani, Mohammed J.,et al. Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice[J]. BIOMACROMOLECULES,2009,10(7):2009-2012.
APA Yang, Sheng-Tao,Wang, Haifang,Meziani, Mohammed J.,Liu, Yuanfang,Wang, Xin,&Sun, Ya-Ping.(2009).Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice.BIOMACROMOLECULES,10(7),2009-2012.
MLA Yang, Sheng-Tao,et al."Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice".BIOMACROMOLECULES 10.7(2009):2009-2012.
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