ICCAS OpenIR
Conjugated Polyelectrolytes as New Platforms for Drug Screening
An, Lingling; Wang, Shu
2009
Source PublicationCHEMISTRY-AN ASIAN JOURNAL
ISSN1861-4728
Volume4Issue:8Pages:1196-1206
AbstractIn recent years, conjugated polyelectrolytes (CPEs) have attracted increasing attention for their applications in highly sensitive biosensors by taking advantage of their unique optical amplification properties. In comparison to previous applications tailored for highly sensitive biomacromolecule detection, this Focus Review highlights recent research efforts in the development of watersoluble CPEs as a new class of optical platforms for the screening of potential drugs. Three types of biological targets for the search of small-molecule active drugs are described: nucleic acids, enzymes, and RNA-protein complexes. Future research directions for drug screening based on CPEs are also presented.
KeywordConjugated Polyelectrolytes Dna Recognition Fluorescent Probes Drug Discovery Sensitivity
DOI10.1002/asia.200900148
Indexed BySCI
Language英语
WOS IDWOS:000269337400003
PublisherWILEY-V C H VERLAG GMBH
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/66138
Collection中国科学院化学研究所
Corresponding AuthorWang, Shu
AffiliationChinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
An, Lingling,Wang, Shu. Conjugated Polyelectrolytes as New Platforms for Drug Screening[J]. CHEMISTRY-AN ASIAN JOURNAL,2009,4(8):1196-1206.
APA An, Lingling,&Wang, Shu.(2009).Conjugated Polyelectrolytes as New Platforms for Drug Screening.CHEMISTRY-AN ASIAN JOURNAL,4(8),1196-1206.
MLA An, Lingling,et al."Conjugated Polyelectrolytes as New Platforms for Drug Screening".CHEMISTRY-AN ASIAN JOURNAL 4.8(2009):1196-1206.
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