ICCAS OpenIR
Electroactive Aniline Pentamer Cross-Linking Chitosan for Stimulation Growth of Electrically Sensitive Cells
Hu, Jun1,2; Huang, Lihong1,2; Zhuang, Xiuli1; Zhang, Peibiao1; Lang, Le1,2; Chen, Xuesi1; Wei, Yen3; Jing, Xiabin1
2008-10-01
Source PublicationBIOMACROMOLECULES
ISSN1525-7797
Volume9Issue:10Pages:2637-2644
AbstractA new kind of electroactive polymers was synthesized by using aniline pentamer (AP) cross-linking chitosan (CS) in acetic acid/DMSO/DMF solution. UV-vis and CV confirmed the electroactivity of polymers in acidic aqueous solution. The amphiphilic polymers self-assembled into 200-300 nm micelles by dialysis against deionized water from the acetic acid buffer solution. Three samples with different weight percentages of AP were used to identify the relationship between the content of AP and the differentiation of rat neuronal pheochromocytoma PC-12 cells without external stimulation. From the results, samples with AP showed an obvious improvement in inducing PC-12 differentiation, while PC-12 on pure CS films had only little neurites on the fifth day; the cells on the films prepared from the samples with 4.9% and 9.5% AP even formed intricate networks. However, the influence of the AP content was the most significant at 4.9 wt % and it decreased when the content increased further.
DOI10.1021/bm800705t
Indexed BySCI ; IC
Language英语
WOS IDWOS:000260049500012
PublisherAMER CHEMICAL SOC
Citation statistics
Cited Times:56[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/64768
Collection中国科学院化学研究所
Corresponding AuthorChen, Xuesi
Affiliation1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Drexel Univ, Dept Chem, Philadelphia, PA 19104 USA
Recommended Citation
GB/T 7714
Hu, Jun,Huang, Lihong,Zhuang, Xiuli,et al. Electroactive Aniline Pentamer Cross-Linking Chitosan for Stimulation Growth of Electrically Sensitive Cells[J]. BIOMACROMOLECULES,2008,9(10):2637-2644.
APA Hu, Jun.,Huang, Lihong.,Zhuang, Xiuli.,Zhang, Peibiao.,Lang, Le.,...&Jing, Xiabin.(2008).Electroactive Aniline Pentamer Cross-Linking Chitosan for Stimulation Growth of Electrically Sensitive Cells.BIOMACROMOLECULES,9(10),2637-2644.
MLA Hu, Jun,et al."Electroactive Aniline Pentamer Cross-Linking Chitosan for Stimulation Growth of Electrically Sensitive Cells".BIOMACROMOLECULES 9.10(2008):2637-2644.
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