ICCAS OpenIR
Stereochemical effect of trans/cis isomers on the aqueous solution properties of acid-labile thermoresponsive polymers
Huang, Xiaonan; Du, Fusheng; Liang, Dehai; Lin, Shrong-Shi; Li, Zichen
2008-07-22
Source PublicationMACROMOLECULES
ISSN0024-9297
Volume41Issue:14Pages:5433-5440
AbstractTwo acid-labile, thermoresponsive poly(methacrylamide)s with the pendant cyclic orthoester moieties of trans and cis configurations, PtNEM and PcNEM, were synthesized via free radical polymerization of the corresponding trans and cis isomers of N-(2-ethoxy-1,3-dioxan-5-yl)methacrylamide (NEM). The thermally induced phase transition/separation behaviors of both polymers as well as the aqueous solution properties below and above their phase transition temperatures were investigated by means of turbidimetry, DSC, H-1 NMR, microscopy, fluorescence probe, and dynamic light scattering. Both PtNEM and PcNEM showed aggregation behaviors below their respective LCSTs, and the former formed more hydrophobic microdomains which had greater capability to solvate pyrene molecules compared with PcNEM. These two polymers exhibited thermally induced sensitive and reversible phase transitions in aqueous solution. PtNEM showed a little lower cloud point but much greater phase transition enthalpy compared to PcNEM. The results of DSC, H-1 NMR, and microscopy measurements revealed that PcNEM exhibited a liquid-liquid phase separation while PtNEM likely underwent a liquid-solid transition. Furthermore, the pH-dependent hydrolyses of both polymers were studied by the H-1 NMR and turbidimetric approaches. The results indicated that both PtNEM and PcNEM showed acid-triggered hydrolysis behaviors, and the hydrolysis products were affected by the configurations of the pendant cyclic groups. On the basis of these results, we can conclude that the stereochemical structures of the pendant cyclic orthoester groups in these poly(methacrylamide)s greatly affect their aqueous solution properties as well as their hydrolysis behaviors.
DOI10.1021/ma800783v
Indexed BySCI
Language英语
WOS IDWOS:000257665900049
PublisherAMER CHEMICAL SOC
Citation statistics
Cited Times:30[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/64748
Collection中国科学院化学研究所
Corresponding AuthorDu, Fusheng
AffiliationPeking Univ, Beijing Natl Lab Mol Sci, Key Lab Polymer Chem & Phys, Minist Educ,Coll Chem & Mol Engn, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Huang, Xiaonan,Du, Fusheng,Liang, Dehai,et al. Stereochemical effect of trans/cis isomers on the aqueous solution properties of acid-labile thermoresponsive polymers[J]. MACROMOLECULES,2008,41(14):5433-5440.
APA Huang, Xiaonan,Du, Fusheng,Liang, Dehai,Lin, Shrong-Shi,&Li, Zichen.(2008).Stereochemical effect of trans/cis isomers on the aqueous solution properties of acid-labile thermoresponsive polymers.MACROMOLECULES,41(14),5433-5440.
MLA Huang, Xiaonan,et al."Stereochemical effect of trans/cis isomers on the aqueous solution properties of acid-labile thermoresponsive polymers".MACROMOLECULES 41.14(2008):5433-5440.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Huang, Xiaonan]'s Articles
[Du, Fusheng]'s Articles
[Liang, Dehai]'s Articles
Baidu academic
Similar articles in Baidu academic
[Huang, Xiaonan]'s Articles
[Du, Fusheng]'s Articles
[Liang, Dehai]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Huang, Xiaonan]'s Articles
[Du, Fusheng]'s Articles
[Liang, Dehai]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.