ICCAS OpenIR
Preparation of polymer-coated mesoporous silica nanoparticles used for cellular imaging by a "graft-from'' method
Yang, Yang1,2; Yan, Xuehai1; Cui, Yue1; He, Qiang1,3; Li, Dongxiang1,3; Wang, Anhe1; Fei, Jinbo1; Li, Junbai1
2008
Source PublicationJOURNAL OF MATERIALS CHEMISTRY
ISSN0959-9428
Volume18Issue:47Pages:5731-5737
AbstractMulti-functional mesoporous silica nanoparticles (MSNs) coated with poly(N-isopropylacrylamide) (PNIPAM) composite nanomaterials have been designed and synthesized by atom transfer radical polymerization (ATRP) on the surface of MSN through the "grafting-from'' approach. Such materials not only provide porous cores which can act as suitable reservoirs, but also possess thermosensitive polymer shells which can entrap hydrophilic guest molecules, like FITC, into the cores upon varying the temperature. The materials can easily carry guest molecules into human breast carcinoma cells (MCF-7) and show little cytotoxicity to the cells. It is demonstrated that such MSN@PNIPAM materials can be applied in biological systems for cellular imaging or as biosensors.
DOI10.1039/b811573g
Indexed BySCI
Language英语
WOS IDWOS:000261745400003
PublisherROYAL SOC CHEMISTRY
Citation statistics
Cited Times:115[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/64142
Collection中国科学院化学研究所
Corresponding AuthorLi, Junbai
Affiliation1.Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid & Interface Sci, BNLMS,Int Joint Lab, Beijing 100190, Peoples R China
2.Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
3.Max Planck Inst Colloids & Interfaces, D-14474 Golm, Germany
Recommended Citation
GB/T 7714
Yang, Yang,Yan, Xuehai,Cui, Yue,et al. Preparation of polymer-coated mesoporous silica nanoparticles used for cellular imaging by a "graft-from'' method[J]. JOURNAL OF MATERIALS CHEMISTRY,2008,18(47):5731-5737.
APA Yang, Yang.,Yan, Xuehai.,Cui, Yue.,He, Qiang.,Li, Dongxiang.,...&Li, Junbai.(2008).Preparation of polymer-coated mesoporous silica nanoparticles used for cellular imaging by a "graft-from'' method.JOURNAL OF MATERIALS CHEMISTRY,18(47),5731-5737.
MLA Yang, Yang,et al."Preparation of polymer-coated mesoporous silica nanoparticles used for cellular imaging by a "graft-from'' method".JOURNAL OF MATERIALS CHEMISTRY 18.47(2008):5731-5737.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yang, Yang]'s Articles
[Yan, Xuehai]'s Articles
[Cui, Yue]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yang, Yang]'s Articles
[Yan, Xuehai]'s Articles
[Cui, Yue]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yang, Yang]'s Articles
[Yan, Xuehai]'s Articles
[Cui, Yue]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.