ICCAS OpenIR
Layer-by-layer assembly of viral capsid for cell adhesion
Lin, Y.1,2; Su, Z.1; Niu, Z.3,4; Li, S.3,4; Kaur, G.3,4; Lee, L. A.3,4; Wang, Q.3,4
2008-07-01
Source PublicationACTA BIOMATERIALIA
ISSN1742-7061
Volume4Issue:4Pages:838-843
AbstractCowpea mosaic virus (CPMV)-based thin films are biologically active for cell culture. Using layer-by-layer assembly of CPMV and poly(diallyldimethylammonium chloride), quantitatively scalable biomolecular surfaces were constructed, which were well characterized using quartz crystal microbalance, UV-vis and atomic force microscopy. The surface coverage of CPMV nanoparticles depended on the adsorption time and pH of the virus solution, with a greater amount of CPMV adsorption occurring near its isoelectric point. It was found that the adhesion and proliferation of NIH-3T3 fibroblasts can be controlled by the coverage of viral particles using this multilayer technique. (c) 2008 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
KeywordCowpea Mosaic Virus Layer-by-layer Self-assembly Cell Adhesion
DOI10.1016/j.actbio.2008.02.026
Indexed BySCI
Language英语
WOS IDWOS:000257266300008
PublisherELSEVIER SCI LTD
Citation statistics
Cited Times:36[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/64138
Collection中国科学院化学研究所
Corresponding AuthorSu, Z.
Affiliation1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Jilin, Peoples R China
2.Jilin Univ, Dept Mat Sci & Engn, Changchun 130025, Peoples R China
3.Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA
4.Univ S Carolina, Nanoctr, Columbia, SC 29208 USA
Recommended Citation
GB/T 7714
Lin, Y.,Su, Z.,Niu, Z.,et al. Layer-by-layer assembly of viral capsid for cell adhesion[J]. ACTA BIOMATERIALIA,2008,4(4):838-843.
APA Lin, Y..,Su, Z..,Niu, Z..,Li, S..,Kaur, G..,...&Wang, Q..(2008).Layer-by-layer assembly of viral capsid for cell adhesion.ACTA BIOMATERIALIA,4(4),838-843.
MLA Lin, Y.,et al."Layer-by-layer assembly of viral capsid for cell adhesion".ACTA BIOMATERIALIA 4.4(2008):838-843.
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