Layer-by-layer assembly of viral capsid for cell adhesion
Lin, Y.1,2; Su, Z.1; Niu, Z.3,4; Li, S.3,4; Kaur, G.3,4; Lee, L. A.3,4; Wang, Q.3,4
AbstractCowpea mosaic virus (CPMV)-based thin films are biologically active for cell culture. Using layer-by-layer assembly of CPMV and poly(diallyldimethylammonium chloride), quantitatively scalable biomolecular surfaces were constructed, which were well characterized using quartz crystal microbalance, UV-vis and atomic force microscopy. The surface coverage of CPMV nanoparticles depended on the adsorption time and pH of the virus solution, with a greater amount of CPMV adsorption occurring near its isoelectric point. It was found that the adhesion and proliferation of NIH-3T3 fibroblasts can be controlled by the coverage of viral particles using this multilayer technique. (c) 2008 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
KeywordCowpea Mosaic Virus Layer-by-layer Self-assembly Cell Adhesion
Indexed BySCI
WOS IDWOS:000257266300008
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Cited Times:36[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorSu, Z.
Affiliation1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Jilin, Peoples R China
2.Jilin Univ, Dept Mat Sci & Engn, Changchun 130025, Peoples R China
3.Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA
4.Univ S Carolina, Nanoctr, Columbia, SC 29208 USA
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GB/T 7714
Lin, Y.,Su, Z.,Niu, Z.,et al. Layer-by-layer assembly of viral capsid for cell adhesion[J]. ACTA BIOMATERIALIA,2008,4(4):838-843.
APA Lin, Y..,Su, Z..,Niu, Z..,Li, S..,Kaur, G..,...&Wang, Q..(2008).Layer-by-layer assembly of viral capsid for cell adhesion.ACTA BIOMATERIALIA,4(4),838-843.
MLA Lin, Y.,et al."Layer-by-layer assembly of viral capsid for cell adhesion".ACTA BIOMATERIALIA 4.4(2008):838-843.
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