ICCAS OpenIR
One-step immobilization of alkanethiol/glycolipid vesicles onto gold electrode: Amperometric detection of Concanavalin A
Guo, Caixin1; Boullanger, Paul2; Jiang, Long1; Liu, Tao1
2008-03-15
Source PublicationCOLLOIDS AND SURFACES B-BIOINTERFACES
ISSN0927-7765
Volume62Issue:1Pages:146-150
AbstractFunctionalized vesicles composed of glycolipid and alkanethiol lipids have been immobilized onto gold surface through one-step self-assembly to construct an electrochemical biosensor for Concanavalin A (Con A) detection. Incorporation of alkanethiol lipid molecules into the vesicles allows for firm attachment of the vesicles onto a gold surface to form a sensing interface. At the same time, the introduction of alkanethiol lipid avoids cumbersome organic syntheses of sulfur-containing compound, making the biosensor greater applied prospect. Through the recognition of Con A by glycolipid which was immobilized on the surface of electrode, a decrease of electrochemical signal was observed. This decrease was restored when the electrode was immersed in a stronger binding solution such as glucose. The repeated usability of the novel sensor is excellent. (c) 2007 Elsevier B.V. All rights reserved.
KeywordBiosensor Con a Alkanethiol/glycolipid Vesicles Electrochemistry
DOI10.1016/j.colsurfb.2007.09.013
Indexed BySCI
Language英语
WOS IDWOS:000255622800023
PublisherELSEVIER SCIENCE BV
Citation statistics
Cited Times:20[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/64092
Collection中国科学院化学研究所
Corresponding AuthorLiu, Tao
Affiliation1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Key Lab Colloid & Interface Sci, Beijing 100080, Peoples R China
2.Univ Lyon 1, CNRS, Lab Chim Organ Glycochim 2, UMR 5246, F-69622 Villeurbanne, France
Recommended Citation
GB/T 7714
Guo, Caixin,Boullanger, Paul,Jiang, Long,et al. One-step immobilization of alkanethiol/glycolipid vesicles onto gold electrode: Amperometric detection of Concanavalin A[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2008,62(1):146-150.
APA Guo, Caixin,Boullanger, Paul,Jiang, Long,&Liu, Tao.(2008).One-step immobilization of alkanethiol/glycolipid vesicles onto gold electrode: Amperometric detection of Concanavalin A.COLLOIDS AND SURFACES B-BIOINTERFACES,62(1),146-150.
MLA Guo, Caixin,et al."One-step immobilization of alkanethiol/glycolipid vesicles onto gold electrode: Amperometric detection of Concanavalin A".COLLOIDS AND SURFACES B-BIOINTERFACES 62.1(2008):146-150.
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