ICCAS OpenIR
An efficient one-pot reaction of indoles, nitroacetate, and paraformaldehyde for the synthesis of tryptophan derivatives
Sui, Yong; Liu, Li; Zhao, Jun-Ling; Wang, Dong; Chen, Yong-Jun
2007-05-28
Source PublicationTETRAHEDRON LETTERS
ISSN0040-4039
Volume48Issue:22Pages:3779-3782
AbstractAn efficient method for the synthesis of tryptophan analogues has been developed via one-pot reaction of commercial available indoles, ethyl nitroacetate, and paraformaldehyde in the presence of molecular sieves. The reaction provided tryptophan nitro-precursors in moderate to good yields, which were further converted to alpha-hydroxymethylated tryptophan derivatives catalyzed by DABCO in high yields. (C) 2007 Elsevier Ltd. All rights reserved.
KeywordTryptophan One-pot Indole Nitroacetate
DOI10.1016/j.tetlet.2007.04.002
Indexed BySCI ; IC ; CCR
Language英语
WOS IDWOS:000246832500004
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Cited Times:19[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/62438
Collection中国科学院化学研究所
Corresponding AuthorLiu, Li
Affiliation1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Biol Chem Lab, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Sui, Yong,Liu, Li,Zhao, Jun-Ling,et al. An efficient one-pot reaction of indoles, nitroacetate, and paraformaldehyde for the synthesis of tryptophan derivatives[J]. TETRAHEDRON LETTERS,2007,48(22):3779-3782.
APA Sui, Yong,Liu, Li,Zhao, Jun-Ling,Wang, Dong,&Chen, Yong-Jun.(2007).An efficient one-pot reaction of indoles, nitroacetate, and paraformaldehyde for the synthesis of tryptophan derivatives.TETRAHEDRON LETTERS,48(22),3779-3782.
MLA Sui, Yong,et al."An efficient one-pot reaction of indoles, nitroacetate, and paraformaldehyde for the synthesis of tryptophan derivatives".TETRAHEDRON LETTERS 48.22(2007):3779-3782.
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