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Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection
Wang, Jian; Hou, Jue; Zhang, Huacheng; Tian, Ye; Jiang, Lei
JAN 17 2018
Source PublicationACS APPLIED MATERIALS & INTERFACES
Volume10Issue:2Pages:2033-2039
AbstractUltrasensitive and selective detection of molecules at nano or sub-nanomolar level is very important for many areas such as early diagnosis and drug testing. Herein, we report a high-sensitive cocaine sensor based on a single nanochannel coupled with DNA aptamers. The single nanochannel-aptamer-based biosensor can recognize cocaine molecules with an excellent sensitivity and good selectivity. A linear relationship between target cocaine concentration and output ionic current is obtained in a wide concentration range of cocaine from 1 nM to 10 mu M. The cocaine sensor also shows a detection limit down to 1 nM. This study provides a new avenue to develop new nanochannel-aptamer-based biosensors for rapid and ultratrace detection of a variety of illicit drugs.
WOS IDWOS:000423140400064
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Cited Times:20[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.iccas.ac.cn/handle/121111/38844
Collection其它
Recommended Citation
GB/T 7714
Wang, Jian,Hou, Jue,Zhang, Huacheng,et al. Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection[J]. ACS APPLIED MATERIALS & INTERFACES,JAN ,10(2):2033-2039.
APA Wang, Jian,Hou, Jue,Zhang, Huacheng,Tian, Ye,&Jiang, Lei.(JAN ).Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection.ACS APPLIED MATERIALS & INTERFACES,10(2),2033-2039.
MLA Wang, Jian,et al."Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection".ACS APPLIED MATERIALS & INTERFACES 10.2(JAN ):2033-2039.
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