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Catalytic asymmetric enamine protonation reaction
Fu, Niankai; Zhang, Long; Luo, Sanzhong
JAN 28 2018
AbstractEnantioselective protonation, delivery of a proton to a carbanion intermediate, is the most straightforward and fundamental method for the preparation of a chiral tertiary carbon stereocenter. Recent efforts for this objective have been realized through enamine catalysis, which has now become a prominent catalytic strategy enabling a range of fascinating chiral transformations. This review will summarize recent advances in the field of enantioselective enamine protonation for the synthesis of optically active carbonyl compounds. Dynamic kinetic resolutions of alpha-substituted carbonyl compounds through enamine intermediates will be discussed as well.
WOS IDWOS:000423400700001
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Fu, Niankai,Zhang, Long,Luo, Sanzhong. Catalytic asymmetric enamine protonation reaction[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,JAN ,16(4):510-520.
APA Fu, Niankai,Zhang, Long,&Luo, Sanzhong.(JAN ).Catalytic asymmetric enamine protonation reaction.ORGANIC & BIOMOLECULAR CHEMISTRY,16(4),510-520.
MLA Fu, Niankai,et al."Catalytic asymmetric enamine protonation reaction".ORGANIC & BIOMOLECULAR CHEMISTRY 16.4(JAN ):510-520.
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