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题名: Covalently Assembled Dipeptide Nanospheres as Intrinsic Photosensitizers for Efficient Photodynamic Therapy in Vitro
作者: Yang, Xiaoke1; Fei, Jinbo1; Li, Qi1; Li, Junbai1
关键词: intrinsic photosensitizer ; nanospheres ; peptides ; photodynamic therapy ; singlet oxygen
刊名: CHEMISTRY-A EUROPEAN JOURNAL
发表日期: 2016-05-04
卷: 22, 期:19, 页:6477-6481
收录类别: SCI
英文摘要: Monodispersed diphenylalanine-based nanospheres with excellent biocompatibility are fabricated through a facile covalent reaction-induced assembly. Interestingly, the nanospheres exhibit red autofluorescence. Most importantly, such assembled dipeptide nanospheres can serve as intrinsic photosensitizer to convert O-2 to singlet oxygen (O-1(2)). Thus, photodynamic therapy in vitro can be achieved effectively. The versatile strategy could be extended to other biomolecules containing a primary amine group for the fabrication of potential intrinsic photosensitizers.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.iccas.ac.cn/handle/121111/36029
Appears in Collections:胶体、界面与化学热力学实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, BNLMS, Beijing 100190, Peoples R China
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