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题名: Detection of volatile organic compounds (VOCs) from exhaled breath as noninvasive methods for cancer diagnosis
作者: Sun, Xiaohua1, 2; Shao, Kang3, 4; Wang, Tie2
关键词: Volatile organic compounds ; Cancer diagnosis ; Exhaled breath ; Sensors
刊名: ANALYTICAL AND BIOANALYTICAL CHEMISTRY
发表日期: 2016-04-01
卷: 408, 期:11, 页:2759-2780
收录类别: SCI
英文摘要: The detection of cancer at an early stage is often significant in the successful treatment of the disease. Tumor cells have been reported to generate unique cancer volatile organic compound (VOC) profiles which can reflect the disease conditions. The detection and analysis of VOC biomarkers from exhaled breath has been recognized as a new frontier in cancer diagnostics and health inspections owing to its potential in developing rapid, noninvasive, and inexpensive cancer screening tools. To detect specific VOCs of low concentrations from exhaled breath, and to enhance the accuracy of early diagnosis, many breath collection and analysis approaches have been developed. This paper will summarize and critically review the exhaled-breath VOC-related sampling, collection, detection, and analytical methods, especially the recent development in VOC sensors. VOC sensors are commonly inexpensive, portable, programmable, easy to use, and can obtain data in real time with high sensitivities. Therefore, many sensor-based VOC detection techniques have huge potential in clinical point-of-care use.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.iccas.ac.cn/handle/121111/36004
Appears in Collections:活体分析化学实验室_期刊论文

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作者单位: 1.China Univ Petr, Inst New Energy, State Key Lab Heavy Oil Proc, Beijing 102249, Peoples R China
2.Chinese Acad Sci, Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Inst Chem, Beijing 100190, Peoples R China
3.Chinese Acad Med Sci, Dept Thorac Surg, Canc Hosp & Inst, Beijing 100021, Peoples R China
4.Peking Union Med Coll, Beijing 100021, Peoples R China
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