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题名: Spectra, stability and labeling of 1-(5-carboxypentyl)-4-(2-(N-ethyl-carbazole-3-yl) vinyl) pyridinium bromide with a large Stokes shift
作者: Gu, Yingchun1, 2; Lin, Dayong3; Li, Ran2; Tang, Yalin1; Fei, Xuening2, 3; Zhou, Jianguo2
关键词: carbazole ; spectra ; large Stokes shift ; stability ; labeling
刊名: LUMINESCENCE
发表日期: 2016-03-01
卷: 31, 期:2, 页:380-387
收录类别: SCI
英文摘要: Carbazole and its derivatives have been widely utilized as a functional building block in the fabrication of the organic medicine, pesticides, materials, etc., because of their excellent solubility, stability and biological activity. In this paper, 1-(5-carboxypentyl)-4-(2-(N-ethyl-carbazole-3-yl) vinyl) pyridinium bromide with a large Stokes shift was synthesized and characterized by H-1 NMR and MS. The UV/vis absorption and fluorescence spectra in different solvents and at different pH values were investigated preliminarily. The photostability and thermostability were also studied and the results showed that the compound was stable. The compound was also used to label bovine serum albumin (BSA) and calf thymus (ct)DNA. The results showed that the fluorescence intensity is enhanced when labeling with BSA and the binding ability is stronger than ctDNA, making it may be used as a biological probe. Copyright (c) 2015 John Wiley & Sons, Ltd.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.iccas.ac.cn/handle/121111/35904
Appears in Collections:分子动态与稳态结构实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Chem, Zhongguancun North First St 2, Beijing 100190, Peoples R China
2.Tianjin Chengjian Univ, Sch Sci, Tianjin 300384, Peoples R China
3.Tianjin Univ, Sch Envirnmental Sci & Engn, Tianjin 300072, Peoples R China
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