中国科学院化学研究所机构知识库
Advanced  
ICCAS OpenIR  > 工程塑料实验室  > 期刊论文
题名: Fabrication, hydrolysis and cell cultivation of microspheres from cellulose-graft-poly( L-lactide) copolymers
作者: Yang, Lili1, 2; Zhang, Jinming1; He, Jiasong1; Zhang, Jun1; Gan, Zhihua3
刊名: RSC ADVANCES
发表日期: 2016
卷: 6, 期:21, 页:17617-17623
收录类别: SCI
英文摘要: Porous microspheres of cellulose-graft-poly(L-lactide) (cellulose-g-PLLA) copolymers were fabricated by a water/oil/water (W/O/W) emulsion evaporation method. Their morphology, hydrophilicity and amount of hydroxyl group content (-OH content) on the surface were adjustable with the change of molar substitution of PLLA (MSPLLA). After a hydrolysis post-processing, surface physical properties of microspheres were regulated further. The influence of physical properties of microspheres on cell cultivation was investigated by setting hepatocellular liver carcinoma cell line (HepG-2) as the example. Compared with the cells on PLLA microspheres, HepG-2 cells with more pseudopods spread well on the surface of cellulose-g-PLLA microspheres. Particularly, the cellulose-g-PLLA microspheres with MSPLLA of 11.5 were the most appropriate candidate for cell adhesion and proliferation. Therefore, a moderate PLLA content of cellulose-g-PLLA copolymers was beneficial to the cell cultivation. This work indicated that combining cellulose with PLLA was an available route to developing cellulose-based materials for cell cultivation.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.iccas.ac.cn/handle/121111/35876
Appears in Collections:工程塑料实验室_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, CAS Key Lab Engn Plast, Beijing 100190, Peoples R China
2.China Univ Petr, State Key Lab Petr Resources & Prospecting, Beijing 102249, Peoples R China
3.Beijing Univ Chem Technol, Coll Life Sci & Technol, State Key Lab Organ Inorgan Composites, Beijing Lab Biomat, Beijing 100029, Peoples R China
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yang, Lili]'s Articles
[Zhang, Jinming]'s Articles
[He, Jiasong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yang, Lili]‘s Articles
[Zhang, Jinming]‘s Articles
[He, Jiasong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院化学研究所 - Feedback
Powered by CSpace