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题名: Observing single nanoparticle events at the orifice of a nanopipet
作者: Li, Ting1, 2; He, Xiulan1, 2; Zhang, Kailin1; Wang, Kai1, 2; Yu, Ping1, 2; Mao, Lanqun1, 2
刊名: CHEMICAL SCIENCE
发表日期: 2016
卷: 7, 期:10, 页:6365-6368
收录类别: SCI
英文摘要: Single nanoparticle (NP) events are successfully observed at the orifice of a nanopipet by blocking the ionic current with a single NP. In addition to the traditional translocation events, we observe both staircase and blip current transients by controlling the radius ratio of NPs to nanopipet or bias potential. Confocal fluorescence microscopy and finite element simulation are used to simultaneously monitor and quantitatively understand these events, respectively. The frequency of the staircase and blip events is proportional to the NP concentration, and could be used for the quantification of NPs. This study offers a new method for NP determination and single NP behavior study.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.iccas.ac.cn/handle/121111/35409
Appears in Collections:活体分析化学实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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