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题名: Hierarchically Staggered Nanostructure of Mineralized Collagen as a Bone-Grafting Scaffold
作者: Liu, Yan1; Liu, Shuai1; Luo, Dan2, 3; Xue, Zhenjie2; Yang, Xinan4; Cu, Lin4; Zhou, Yanheng1; Wang, Tie2
刊名: ADVANCED MATERIALS
发表日期: 2016-10-19
卷: 28, 期:39, 页:8740-8748
收录类别: SCI
英文摘要: A hierarchical, intrafibrillarly mineralized collagen (HIMC) is achieved through a selective mineralization progress in the collagenous gap regions mediated by poly(acrylic acid) with appropriate molecular weight. The associated topographical features directly correlate with nanomechanical heterogeneities of the HIMC to accommodate a broad range of external loads. Moreover, this hierarchically staggered nanostructure provides an optimized microenvironment to improve bone regeneration by instructing host cells.
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.iccas.ac.cn/handle/121111/35127
Appears in Collections:活体分析化学实验室_期刊论文

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作者单位: 1.Peking Univ Sch & Hosp Stomatol, Ctr Craniofacial Stem Cell Res & Regenerat, Natl Engn Lab Digital & Mat Technol Stomatol, Beijing Key Lab Digital Stomatol,Dept Orthodont,, Beijing 100081, Peoples R China
2.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Inst Chem, Beijing 100190, Peoples R China
3.China Univ Petr, Inst New Energy, State Key Lab Heavy Oil Proc, Beijing 102249, Peoples R China
4.Chinese Acad Sci, Inst Phys, Beijing 100190, Peoples R China
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